Product Name:hIRBP651-670
CAS No.:N/A
Synonyms:IRBP (651-670) (human);人光感受器間類視黃醇結(jié)合蛋白 (IRBP)片段多肽
Catalog No.:218P338
Brand:HongTide(上海鴻肽生物)
Description:hIRBP651-670是人光感受器間類視黃醇結(jié)合蛋白 (IRBP) 的氨基酸殘基 651 至 670,多肽序列中含有20個(gè)氨基酸,已被鑒定為新的葡萄膜生成表位。hIRBP651-670對 H-2b 單倍型小鼠具有致葡萄膜炎性,并在C57BL/6小鼠中引起實(shí)驗(yàn)性自身免疫性葡萄膜炎(EAU),其嚴(yán)重程度和發(fā)生率高于先前表征的 IRBP(1-20)(人 ) 表位。 與 IRBP (1-20)(人)和 IRBP (651-670) 人共同免疫是相加的,但不是協(xié)同的。hIRBP651-670似乎是從天然 IRBP 的保守區(qū)域自然加工的表位。
HIRBP651-670 is the amino acid residue 651-670 of human photoreceptor Retinol like binding protein (IRBP). The peptide sequence contains 20 amino acids and has been identified as a new Uvea generating epitope. HIRBP651-670 has Uveitis inducing effect on H-2b Haplotype mice, and causes experimental autoimmune Uveitis (EAU) in C57BL/6 mice. Its severity and incidence are higher than previously characterized IRBP (1-20) (human) epitope. The co immunity with IRBP (1-20) and IRBP (651-670) individuals is additive, but not synergistic. HIRBP651-670 seems to be a naturally processed epitope from the conserved region of natural IRBP.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility:H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | LAQGAYRTAVDLESLASQLT |
Sequence(3-letter code) | H-Leu-Ala-Gln-Gly-Ala-Tyr-Arg-Thr-Ala-Val-Asp-Leu-Glu-Ser-Leu-Ala-Ser-Gln-Leu-Thr-OH |
Peptide Structure |
|
Molecular Formula | C91H151N25O32 |
Molecular Weight | 2107.35 |
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關(guān)鍵字: 內(nèi)源性肽激活劑多肽;hIRBP651-670;IRBP (651-670) (huma;多肽;多肽合成;
上海鴻肽生物科技有限公司(簡稱:鴻肽生物)是一家以多肽以及多肽上下游產(chǎn)品研發(fā)、生產(chǎn)、銷售以及技術(shù)轉(zhuǎn)讓為主要業(yè) 務(wù)科技公司。公司現(xiàn)有產(chǎn)品涵蓋:定制多肽、目錄多肽、氨基酸衍生物、小分子化合物;公司自成立以來,秉持“用質(zhì)量作船, 以服務(wù)為帆,為科研服務(wù)”的企業(yè)理念,為國內(nèi)外眾多科研工作者提供了優(yōu)質(zhì)的服務(wù)及產(chǎn)品。