Host:Rabbit
Target Protein:Collagen XVII
IR:Immunogen Range:1300-1450/1497
Clonality:Monoclonal
Isotype:IgG
Entrez Gene:1308
Swiss Prot:Q9UMD9
Source:Recombinant human Collagen XVII protein:1300-1450/1497
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene encodes the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. Mutations in this gene are associated with both generalized atrophic benign and junctional epidermolysis bullosa. Two homotrimeric forms of type XVII collagen exist. The full length form is the transmembrane protein. A soluble form, referred to as either ectodomain or LAD-1, is generated by proteolytic processing of the full length form. [provided by RefSeq, Jul 2008
Size:50ul
Concentration:1mg/1ml
Applications:WB(1:500-2000)
IHC-P(1:50-200)
IHC-F(1:50-200)
ICC(1:50)
IF(1:50-200)
Cross Reactive Species:Human
Mouse
Rat
本產(chǎn)品僅供科研使用。不能用于人和動物治療等其它臨床診斷使用！
關(guān)鍵字： BPAG2;BPAG 2;FLJ60881;KIAA0204;LAD;
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