Host:Rabbit
Target Protein:phospho-CDKN1B (Thr157)
IR:Immunogen Range:PA(p-T)DD
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:1027
Swiss Prot:P46527
Source:KLH conjugated Synthesised phosphopeptide derived from human CDKN1B around the phosphorylation site of Thr157:PA(p-T)DD
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. [provided by RefSeq, Jul 2008]
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
Flow-Cyt(1μg/Test)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Rabbit
Guinea Pig
本產(chǎn)品僅供科研使用。不能用于人和動(dòng)物治療等其它臨床診斷使用!
關(guān)鍵字: p27;KIP1;KIP 1;MEN1B;CDKN4;
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