Host:Rabbit
Target Protein:Notch3
IR:Immunogen Range:2001-2100/2318
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:18131
Swiss Prot:Q61982
Source:KLH conjugated synthetic peptide derived from mouse Notch3:2001-2100/2318
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). [provided by RefSeq, Jul 2008]
Size:50ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
Flow-Cyt(1ug/Test)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
本產品僅供科研使用。不能用于人和動物治療等其它臨床診斷使用！
關鍵字： Notch3;CADASIL;CASIL;Notch homolog 3;Notch 3;
上海滬震實業(yè)有限公司是一家集研發(fā)、生產和銷售于一體的生命科學實驗室產品生物科技企業(yè)。主營產品：試劑盒，ELISA試劑盒，抗體，重組蛋白，血清，胎牛血清，細胞，原代細胞 細胞培養(yǎng)試劑，常用生化試劑。