Host:Rabbit
Target Protein:AGR2
IR:Immunogen Range:
Clonality:Monoclonal
Isotype:IgG
Entrez Gene:10551
Swiss Prot:O95994
Source:KLH conjugated synthetic peptide derived from human AGR2:
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:AGR2 is a member of the anterior gradient homolog family. It is the human ortholog of XAG-2, the secreted Xenopus laevis Anterior Gradient protein. In X. laevis, it is involved in cement gland differentiation and neural marker gene expression. AGR2 is a secretory protein encoded by two different AGR2 transcripts. It interacts with LYPD3 and ?dystroglycan (DAG-1). AGR2 is ubiquitously expressed with up-regulated expression in prostate cancer, breast cancer, lung cancer, renal carcinomas and endometrial carcinomas. AGR2 expression is positively correlated with that of the estrogen receptor (ER) and is negatively correlated with that of the epidermal growth factor receptor (EGFR). AGR2 may serve as a potential therapeutic marker for various cancers.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:1000-5000)
IP(1:20-100)
IHC-P(1:50-200)
IHC-F(1:50-200)
ICC(1:50-200)
Cross Reactive Species:Human
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本產(chǎn)品僅供科研使用。不能用于人和動物治療等其它臨床診斷使用！
關(guān)鍵字： AGR2;HAG2;GOB4;HAG 2;HAG-2;
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