Host:Rabbit
Target Protein:SCARB1/Scavenger Receptor BI
IR:Immunogen Range:
Clonality:Monoclonal
Isotype:IgG
Entrez Gene:949
Swiss Prot:Q8WTV0
Source:KLH conjugated synthetic peptide derived from human SCARB1/Scavenger Receptor BI:
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:High density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis. The SR-BI (Scavenger Receptor BI) protein binds HDLs and mediates selective uptake of HDL cholesteryl ester. SR-BI binds HDL with high affinity, is expressed primarily in liver and nonplacental steroidgenic tissues, and mediates selective cholesterol uptake by a distinct mechanism. In mice, it seems that SR-BI plays a key role in determining the levels of plasma lipoprotein cholesterol and the accumulation of cholesterol stores in the adrenal gland. Scavenging Receptor SR-BI plays a critical role in HCV attachment and/or cell entry by interacting with HCV E1/E2 glycoproteins heterodimer.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
IHC-P(1:200-500)
IHC-F(1:200-500)
ICC(1:50-200)
Cross Reactive Species:Human
Mouse
Rat
本產(chǎn)品僅供科研使用。不能用于人和動(dòng)物治療等其它臨床診斷使用！
關(guān)鍵字： HDL-R;CLA1;CLA 1;SRB1;SR B1;
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