產(chǎn)品屬性：
產(chǎn)品名稱 | 規(guī)格 | CAS號(hào) | 型號(hào) |
Colcemid | 1mg 5mg 10mg 50mg | 477-30-5 | EY-Y0165587 |
Cas No.477-30-5
別名 N/A
化學(xué)名 (7S)-6,7-dihydro-1,2,3,10-tetramethoxy-7-(methylamino)-benzo[a]heptalen-9(5H)-one
分子式 C21H25NO5
分子量 371.4
溶解度 30mg/mL in ethanol, 25mg/mL in DMSO or DMF
儲(chǔ)存條件 Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述：
Reference:
[1]. Muzaffar, A., Brossi, A., Lin, C.M., et al. Antitubulin effects of derivatives of 3-demethylthiocolchicine, methylthio ethers of natural colchicinoids, and thioketones derived from thiocolchicine. Comparison with colchicinoids. J. Med. Chem. 33(2), 567-571 (1990).
[2]. Rieder, C.L., and Palazzo, R.E. Colcemid and the mitotic cycle. Journal of Cell Science 102(3), 387-392 (1992).
[3]. Jordan, M.A., and Wilson, L. Microtubules as a target for anticancer drugs. Nature Reviews.Cancer 4(4), 253-265 (2004).
[4]. Curlej, J., Bulla, J., and Chrenek, P. Occurrence of chromosomal aneuploidy in rabbit oocytes and embryos at different developmental stages. Zygote 18(3), 203-207 (2010).
[5]. Yang, H., Ganguly, A., and Cabral, F. Inhibition of cell migration and cell division correlates with distinct effects of microtubule inhibiting drugs. The Journal of Biological Chemisty 285(42), 32242-32250 (2010).
[6]. Bayani, J., and Squire, J.A. Preparation of cytogenetic specimens from tissue samples. Current Protocols in Cell Biology 22(22.2), 1-15 (2004).
[]7. Sablina, A.A., Chumakov, P.M., Levine, A.J., et al. p53 activation in response to microtubule disruption is mediated by integrin-Erk signaling. Oncogene 20(8), 899-909 (2001).
關(guān)鍵字： 477-30-5;C21H25NO5;Colcemid;
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