中文名稱:Diprotin A | 英文名稱:Diprotin A |
CAS:90614-48-5 | 品牌: 一研 |
保存條件: Store at -20°C | 產(chǎn)品類別: 抑制劑 |
Cas : 90614-48-5 |
產(chǎn)品屬性:
產(chǎn)品名稱 | 規(guī)格 | CAS號(hào) | 型號(hào) |
Diprotin A | 10mg 25mg 50mg 100mg | 90614-48-5 | EY-Y0164680 |
Cas No.90614-48-5
別名 N/A
化學(xué)名 N/A
分子式 C17H31N3O4
分子量 341.5
溶解度 DMF: 33 mg/ml,DMSO: 25 mg/ml,Ethanol: 10 mg/ml,PBS (pH 7.2): 10 mg/ml
儲(chǔ)存條件 Store at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
產(chǎn)品描述:
Diprotin A is a tripeptide inhibitor of dipeptidyl peptidase 4 (DPP-4; IC50 = 1.1 μg/ml).1 It inhibits degradation of glucagon-like peptide 1 in culture with insulin-secreting BRIN-BD11 rat pancreatic β-cells when used at a concentration of 25 μM.2 Diprotin A (5 mg/ml) pre-incubation enhances chemotaxis of murine embryonic stem cells towards stromal cell-derived factor-1 (SDF-1/CXCL12) in vitro.3 Pre-incubation of CD34+ human umbilical cord blood cells with diprotin A (5 mM) prior to injection increases engraftment in NOD/SCID recipient mice.4
References
1. Umezawa, H., Aoyagi, T., Ogawa, K., et al. Diprotins A and B, inhibitors of dipeptidyl aminopeptidase IV, produced by bacteria. J. Antibiot. (Tokyo) 37(4), 422-425 (1984).
2. Green, B.D., Liu, H.K., McCluskey, J.T., et al. Function of a long-term, GLP-1-treated, insulin-secreting cell line is improved by preventing DPP IV-mediated degradation of GLP-1. Diabetes Obes. Metab. 7(5), 563-569 (2005).
3. Guo, Y., Hangoc, G., Bian, H., et al. SDF-1/CXCL12 enhances survival and chemotaxis of murine embryonic stem cells and production of primitive and definitive hematopoietic progenitor cells. Stem Cells 23(9), 1324-1332 (2005).
4. Campbell, T.B., Hangoc, G., Liu, Y., et al. Inhibition of CD26 in human cord blood CD34+ cells enhances their engraftment of nonobese diabetic/severe combined immunodeficiency mice. Stem Cells Dev. 16(3), 347-354 (2007).
成立日期 | 2014-06-05 (11年) | 注冊(cè)資本 | 100 |
員工人數(shù) | 50-100人 | 年?duì)I業(yè)額 | ¥ 100萬(wàn)以內(nèi) |
主營(yíng)行業(yè) | 生化試劑,抗體,細(xì)胞培養(yǎng),分子生物學(xué),免疫安全 | 經(jīng)營(yíng)模式 | 工廠,試劑 |
產(chǎn)品名稱 | 價(jià)格 | 公司名稱 | 報(bào)價(jià)日期 | |
---|---|---|---|---|
詢價(jià) |
VIP8年
|
成都云?;び邢薰?/div>
|
2024-12-25 | |
詢價(jià) |
VIP3年
|
紹興市均宇生物科技有限公司
|
2024-12-25 | |
詢價(jià) |
VIP2年
|
上海鴻肽生物科技有限公司
|
2024-12-17 | |
¥143 |
VIP3年
|
TargetMol中國(guó)(陶術(shù)生物)
|
2024-12-12 | |
詢價(jià) |
VIP5年
|
南昌探真生物技術(shù)有限公司
|
2024-10-21 | |
詢價(jià) |
VIP2年
|
上海拓旸生物科技有限公司
|
2024-08-26 | |
¥1796.47 |
VIP10年
|
西格瑪奧德里奇(上海)貿(mào)易有限公司
|
2023-10-27 |