中文名稱

N-[（1S，2R，3E）-2-羥基-1-（羥甲基）-3-十七碳烯-1-基]-辛酰胺； N-辛?；拾贝迹?C-8神經(jīng)酰胺

英文名字

N-[（1S，2R，3E）-2-hydroxy-1-（hydroxymethyl）-3-heptadecen-1-yl]-octanamide； N-octanoylsphingosine； C-8 Ceramide

供應(yīng)商

開(kāi)曼生物

產(chǎn)品貨號(hào)

62540-10

背景資料

C-8 ceramide is a cell-permeable analog of naturally occurring ceramides. Unlike C-2 ceramide， it is metabolized within cells to generate natural ceramides， often causing a dramatic increase in cellular ceramide levels. For this reason， treatment of cells with C-8 ceramide may more closely mimic the effects of ceramide elevation than does treatment with shorter chain ceramide analogs. C-8 ceramide likely mediates many diverse biological activities， as do natural ceramides. It promotes the differentiation of human keratinocytes and induces apoptosis of both human leukemia cells and the U937 cell line.

產(chǎn)品描述

C-8 ceramide is a cell-permeable analog of naturally occurring ceramides. Unlike C-2 ceramide， it is metabolized within cells to generate natural ceramides， often causing a dramatic increase in cellular ceramide levels.{5258} For this reason， treatment of cells with C-8 ceramide may more closely mimic the effects of ceramide elevation than does treatment with shorter chain ceramide analogs. C-8 ceramide likely mediates many diverse biological activities， as do natural ceramides. It promotes the differentiation of human keratinocytes{5185} and induces apoptosis of both human leukemia cells and the U937 cell line.{5258，4667}

保存建議

建議您在收到開(kāi)曼生物品牌的C-8 Ceramide （10 mg）產(chǎn)品后置于-20度保存，產(chǎn)品有效期為365天.

其他

開(kāi)曼生物向全球科學(xué)工作者提供多研究領(lǐng)域的生化、免疫試劑和分析試劑盒，其產(chǎn)品被廣泛應(yīng)用于腫瘤、氧化氮、神經(jīng)學(xué)、凋亡、氧化性損傷、內(nèi)分泌學(xué)等不同研究領(lǐng)域.開(kāi)曼生物可提供用于檢測(cè)的特色試劑盒，如：類花生酸類物質(zhì)、游離的生物標(biāo)志、環(huán)核苷、激素及氧化氮等；也提供多種高質(zhì)量試劑，包括：類花生酸類物質(zhì)、氧化氮試劑及許多相關(guān)脂質(zhì)、脂肪酸、酶和抗體