Tyrphostin AG1433 NEW
Price | $44 | $98 | $163 |
Package | 1mg | 5mg | 10mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-19 |
Product Details
Product Name: Tyrphostin AG1433 | CAS No.: 168835-90-3 |
Purity: 97.51% | Supply Ability: 10g |
Release date: 2024/11/19 |
Product Introduction
Bioactivity
Name | Tyrphostin AG1433 |
Description | Tyrphostin AG1433 (AG1433) is an inhibitor of tyrosine kinases and also a dual inhibitor of PDGFRβ(IC50s = 5.0 μM) and VEGFR-2 (Flk-1/KDR)(IC50s = 9.3 μM). |
In vitro | In glioblastoma cells, Tyrphostin AG1433 (0.1-100 μM; 72 hours; GB8B cells) treatment induces moderate cytotoxicity [1]. |
In vivo | Tyrphostin AG1433 is prepared in methylcellulose pellets and applies to the CAMs of 4-6-day-old chicken embryos, and prevents the formation of new yessels under the pellets[2]. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 3.06 mg/mL (11.47 mM), Sonication is recommended. |
Keywords | cytotoxicity | PDGFRβ | Tyrphostin AG-1433 | VEGFR | kinases | Vascular endothelial growth factor receptor | SU 1433 | Tyrphostin AG1433 | Tyrphostin AG 1433 | Platelet-derived growth factor receptor | AG-1433 | angiogenesis,tyrosine | inhibit | AG 1433 | VEGFR-2 | Inhibitor | ATM | SU-1433 | PDGFR |
Inhibitors Related | Ribociclib | Nintedanib | Regorafenib monohydrate | Imatinib Mesylate | Sorafenib | Regorafenib | Sanguinarine chloride | Sorafenib tosylate | Lenvatinib mesylate | Imatinib | Pazopanib | Axitinib |
Related Compound Libraries | Anti-Pancreatic Cancer Compound Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Kinase Inhibitor Library | Tyrosine Kinase Inhibitor Library | Anti-Breast Cancer Compound Library | Inhibitor Library | Anti-Cardiovascular Disease Compound Library | Bioactive Compounds Library Max | Anti-Liver Cancer Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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