I-OMe-Tyrphostin AG 538 NEW
Price | $51 | $122 | $197 |
Package | 1mg | 5mg | 10mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-06 |
Product Details
Product Name: I-OMe-Tyrphostin AG 538 | CAS No.: 1094048-77-7 |
Purity: 96.66% | Supply Ability: 10g |
Release date: 2024/11/06 |
Product Introduction
Bioactivity
名稱 | I-OMe-Tyrphostin AG 538 |
描述 | I-OMe-Tyrphostin AG 538 is a specific IGF-1R inhibitor and ATP-competitive inhibitor of PI5P4Kα (IC50: 1 μM).I-OMe-Tyrphostin AG 538 inhibits IGF-1R-mediated signaling and exhibits preferential cytotoxicity to nutrient-deficient PANC1 cells. |
體外活性 | I-OMe Tyrhost AG 538 (0-3 μM; 1 hour) can prevent the phosphorylation of Akt, IGF-1R, and Erk.[1] I-OMe Tyrphostin AG 538 (0.1-1000 μM; 24 hours) has cytotoxicity on PANC-1 cells in nutrient deficient culture medium.[1] |
存儲(chǔ)條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | DMSO : 50 mg/mL (114.37 mM), Sonication is recommended. |
關(guān)鍵字 | I-OMe-Tyrphostin AG-538 | I-OMe-Tyrphostin AG 538 | I-OMe-AG538 | I-OMe-AG-538 | I-OMe-Tyrphostin AG538 |
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相關(guān)庫 | 經(jīng)典已知活性庫 | 膜蛋白靶向化合物庫 | 激酶抑制劑庫 | 酪氨酸激酶分子庫 | 抗肥胖化合物庫 | 抑制劑庫 | 抗衰老化合物庫 | 已知活性化合物庫 | 共價(jià)抑制劑庫 | 抗癌化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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