Tucidinostat (Chidamide) NEW
Price | Get Latest Price |
Package | 25kg |
Min. Order: | 1kg |
Supply Ability: | 2000ton |
Update Time: | 2024-04-12 |
Product Details
Product Name: Tucidinostat (Chidamide) | CAS No.: 1616493-44-7 |
Min. Order: 1kg | Purity: 99% |
Supply Ability: 2000ton | Release date: 2024/04/12 |
Appearance: White powder |
Tucidinostat (Chidamide, HBI-8000, CS-055) is a low molar concentration inhibitor of HDAC1, 2, 3, and 10 with IC50 of 95, 160, 67, and 78 nM, respectively. Chidamide inhibits HDACs1-3 type I and HDAC10 type IIb. In human cervical adenocarcinoma Hela cells and human PBMC cells, Chidamide significantly induced histone H3 acetylation. In the micromolar concentration range, Chidamide and MS-275 inhibited cell growth in most human tumor cell lines, but not in all tumor cells tested (a total of 18 were tested). In human embryonic kidney (CCC-HEK) and human embryonic liver (CCC-HEL), the toxic effects of Chidamide on normal cells were significantly reduced compared with MS-275, indicating the difference in the cytotoxic effects of Chidamide on normal cells and cancer cells.
Storage Condition | Keep in a cool and dry place |
Transportation | By Sea or by Air(DHL/UPS/TNT/FEDEX/EMS) |
Delivery Time | 7-28 days |
Payment | T/T, Western Union or Bitcoin |
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- Since: 2020-08-05
- Address: 804, Unit 2, Building 4, i City, No. 11, South Tangyan Road, High-tech Zone, Xi 'an, Shaanxi