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Postion:Product Catalog >RO1138452
RO1138452
  • RO1138452

RO1138452 NEW

Price $44 $63 $97
Package 1mg 2mg 5mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-07

Product Details

Product Name: RO1138452 CAS No.: 221529-58-4
Purity: 99.34% Supply Ability: 10g
Release date: 2024/11/07

Product Introduction

Bioactivity

名稱RO1138452
描述RO1138452 (CAY10441) is a selective and orally bioavailable antagonist of prostacyclin receptor (pKi: 8.3). It antagonizes the carbaprostacyclin-induced activation of human neuroblastoma adenylate cyclase, blocking cyclic AMP accumulation in a dose-dependent manner. Likewise, it inhibits the binding of tritiated iloprost to rodent neuroblastoma cells with a Ki of about 1.5 nM. At levels between 2-20 mg/kg in rats, CAY10441 shows significant analgesic activity in standard antinociceptive assays [1].
存儲(chǔ)條件store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度DMSO : 45 mg/mL (145.44 mM)
關(guān)鍵字RO-1138452 | CAY 10441 | CAY-10441 | Inhibitor | inhibit | RO1138452 | RO 1138452 | Prostaglandin Receptor
相關(guān)產(chǎn)品Angoroside C | Pranoprofen | Tranilast | Benorilate | Rutin | Ozagrel | Ethamsylate | Rebamipide | Evodiamine | Tebufelone | Timapiprant | p-Hydroxycinnamic acid
相關(guān)庫(kù)經(jīng)典已知活性庫(kù) | 疼痛相關(guān)化合物庫(kù) | 膜蛋白靶向化合物庫(kù) | 抑制劑庫(kù) | 內(nèi)分泌激素分子庫(kù) | NO PAINS 化合物庫(kù) | 口服活性化合物庫(kù) | 已知活性化合物庫(kù) | 活性脂質(zhì)化合物庫(kù) | GPCR靶點(diǎn)分子庫(kù)

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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