Solifenacin NEW
| Price | $39 | $58 | $93 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Solifenacin | CAS No.: 242478-37-1 |
| Purity: 99.87% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Solifenacin |
| Description | Solifenacin (YM905 free base) (YM905 free base) is a novel muscarinic receptor antagonist, its pKis for M1, M2 and M3 receptors is of 7.6, 6.9 and 8.0, respectively. |
| In vivo | Solifenacin exerts minimal inhibitory effects on salivary and cardiac responses at a dosage of 630 nmol/kg (0.3 mg/kg), achieving inhibition levels of 66% and 49%, respectively, at 2100 nmol/kg (1 mg/kg). At lower doses (63 and 210 nmol/kg or 0.03 and 0.1 mg/kg), Solifenacin slightly enhances saliva secretion. Conversely, it reduces bladder responses by 40% at 210 nmol/kg (0.1 mg/kg) and completely suppresses them at 2100 nmol/kg (1 mg/kg). Intravenously administered, Solifenacin (0.01 to 0.3 mg/kg) progressively augments bladder capacity and the volume of urine voided when dosed at 0.03 mg/kg or higher, without impacting residual volume or micturition pressure at any administered dosage. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 55 mg/mL (151.74 mM), Sonication is recommended. H2O : < 0.1 mg/mL (insoluble) |
| Keywords | Muscarinic acetylcholine receptor | Solifenacin | YM905 | mAChR | YM 905 | Inhibitor | inhibit | YM-905 |
| Inhibitors Related | Adiphenine hydrochloride | Nanofin | Arecoline hydrobromide | Forskolin | CLOZAPINE N-OXIDE | Pilocarpine nitrate | Ribavirin | Adenine | Choline chloride | Propoxur |
| Related Compound Libraries | Bioactive Compound Library | Anti-Neurodegenerative Disease Compound Library | Approved Drug Library | Membrane Protein-targeted Compound Library | ReFRAME Related Library | Drug Repurposing Compound Library | Inhibitor Library | FDA-Approved Drug Library | Orally Active Compound Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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