PI4KIIIbeta-IN-9 NEW
Price | $73 | $198 | $297 |
Package | 1mg | 5mg | 10mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-09 |
Product Details
Product Name: PI4KIIIbeta-IN-9 | CAS No.: 1429624-84-9 |
Purity: 97.18% | Supply Ability: 10g |
Release date: 2024/11/09 |
Product Introduction
Bioactivity
名稱 | PI4KIIIbeta-IN-9 |
描述 | PI4KIIIbeta-IN-9 is a potent inhibitor of PI4KIIIβ [IC50 of 7 nM]. |
體外活性 | PI4KIIIbeta-IN-9 (Compound 9) exhibits weak inhibition of PI3KC2γ (IC50 ~1 μM), PI3Kα (~2 μM), and PI4KIIIα (~2.6 μM), with less than 50% inhibition up to 20 μM for PI4K2α, PI4K2β, and PI3Kβ. It conforms to the active site of PI4KIIIβ, forming extensive contacts, and inhibits PI3Kδ and PI3Kγ with IC50 values of 152 nM and 1046 nM, respectively. |
存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | DMSO : 4.88 mg/mL (10 mM), Sonication is recommended. |
關(guān)鍵字 | PI4 kinases | inhibit | Inhibitor | Phosphatidylinositol 4 kinases | PI4K | PI3K | PI4KIIIbetaIN9 | PI4KIIIb-IN-9 | Phosphoinositide 3-kinase | PI4KIIIβ-IN-9 | PI-4KIIIbeta-IN-9 | PI4KIIIbeta IN 9 | PI4KIIIbeta-IN-9 |
相關(guān)產(chǎn)品 | Myricetin | Erucic acid | Sapanisertib | (2S,3R,4S)-4-Hydroxyisoleucine | Duvelisib (R enantiomer) hydrochloride | Isoprenaline hydrochloride | Quercetin | GDC0084 | Quercetin Dihydrate | Apilimod | LY294002 | Idelalisib |
相關(guān)庫 | 抗肺癌化合物庫 | 抗胰腺癌化合物庫 | 經(jīng)典已知活性庫 | 激酶抑制劑庫 | 抗乳腺癌化合物庫 | 血管生成庫 | 抑制劑庫 | 代謝化合物庫 | 抗衰老化合物庫 | 已知活性化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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