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Postion:Product Catalog >PI4KIIIbeta-IN-10
PI4KIIIbeta-IN-10
  • PI4KIIIbeta-IN-10

PI4KIIIbeta-IN-10 NEW

Price $73 $167 $268
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-12

Product Details

Product Name: PI4KIIIbeta-IN-10 CAS No.: 1881233-39-1
Purity: 99.85% Supply Ability: 10g
Release date: 2024/11/12

Product Introduction

Bioactivity

名稱PI4KIIIbeta-IN-10
描述PI4KIIIbeta-IN-10 is a potent inhibitor of PI4KIIIβ with an IC50 value of 3.6 nM.
體外活性The most potent of these molecules (PI4KIIIbeta-IN-10;compound 10) was screened over a panel of nine related lipid kinases and was >200 fold selective for PI4KIIIβ across all enzymes tested. Two of the most potent and selective molecules (compound 9+10) were also the most effective antiviral compounds in a cellular model of Hepatitis C virus replication, with the best balance of antiviral potency and low cellular toxicity. PI4KIIIbeta-IN-10 shows weak inhibition of PI3KC2γ (IC50 ~1 μM), PI3Kα (~10 μM), and PI4KIIIα (~3 μM), and <20% inhibition at concentrations up to 20 μM for PI4K2α, PI4K2β, and PI3Kβ[1].
存儲條件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度DMSO : 30 mg/mL (63.08 mM)
關(guān)鍵字inhibit | Phosphatidylinositol 4 kinases | Inhibitor | PI4 kinases | PI4K | PI4KIIIβ-IN-10 | PI4KIIIbetaIN10 | PI-4KIIIbeta-IN-10 | PI4KIIIb-IN-10 | PI4KIIIbeta IN 10 | PI4KIIIbeta-IN-10
相關(guān)產(chǎn)品Myricetin | Erucic acid | Sapanisertib | (2S,3R,4S)-4-Hydroxyisoleucine | Duvelisib (R enantiomer) hydrochloride | Isoprenaline hydrochloride | Quercetin | GDC0084 | Quercetin Dihydrate | Apilimod | LY294002 | Idelalisib
相關(guān)庫神經(jīng)再生化合物庫 | 經(jīng)典已知活性庫 | HIF-1化合物庫 | 激酶抑制劑庫 | 抗癌細(xì)胞代謝庫 | 抑制劑庫 | 干細(xì)胞分化化合物庫 | 腫瘤免疫治療小分子化合物庫 | 抗衰老化合物庫 | 已知活性化合物庫

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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