Product Details
Product Name:
PCO371 |
CAS No.:
1613373-33-3 |
Purity:
99.25% |
Supply Ability:
10g |
Release date:
2024/11/14 |
Product Introduction
Bioactivity
名稱 | PCO371 |
描述 | PCO371 (2,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro(4.5)dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-5,5-dimethyl-) is an orally active full agonist of parathyroid hormone receptor 1. It has no effect on PTH type 2 receptor. |
體外活性 | In COS-7 cells expressing hPTHR1, PCO371 causes cAMP production (EC50: 2.4?μM). 2.5 μM in COS-7 cells transfected with hPTHR1-delNT, and also enhances the phospholipase C activity (EC50, 17?μM)[1]. |
存儲條件 | keep away from direct sunlight,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | DMSO : 120 mg/mL (188.78 mM), Sonication is recommended.
|
關(guān)鍵字 | PCO371 | PCO-371 | inhibit | Inhibitor | THR | PCO 371 | Thyroid Hormone Receptor |
相關(guān)產(chǎn)品 | Propylthiouracil | Liothyronine | L-Thyroxine | L-Thyroxine sodium | 2,2-BIS(2-HYDROXY-5-BIPHENYLYL)PROPANE | Resmetirom | DS08210767 | Carbimazole | Methimazole | Liothyronine sodium | 2-Thiouracil | Tiratricol |
相關(guān)庫 | 經(jīng)典已知活性庫 | 藥物功能重定位化合物庫 | NO PAINS 化合物庫 | 內(nèi)分泌激素分子庫 | 已知活性化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
Product name |
Price |
|
Suppliers |
Update time |
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$/ |
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Anhui Ruihan Technology Co., Ltd
|
2023-08-21 |