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Postion:Product Catalog >Biochemical Engineering>Biochemical Reagents>PCO371
PCO371
  • PCO371

PCO371 NEW

Price $97 $247 $396
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-14

Product Details

Product Name: PCO371 CAS No.: 1613373-33-3
Purity: 99.25% Supply Ability: 10g
Release date: 2024/11/14

Product Introduction

Bioactivity

名稱PCO371
描述PCO371 (2,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro(4.5)dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-5,5-dimethyl-) is an orally active full agonist of parathyroid hormone receptor 1. It has no effect on PTH type 2 receptor.
體外活性In COS-7 cells expressing hPTHR1, PCO371 causes cAMP production (EC50: 2.4?μM). 2.5 μM in COS-7 cells transfected with hPTHR1-delNT, and also enhances the phospholipase C activity (EC50, 17?μM)[1].
存儲條件keep away from direct sunlight,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度DMSO : 120 mg/mL (188.78 mM), Sonication is recommended.
關(guān)鍵字PCO371 | PCO-371 | inhibit | Inhibitor | THR | PCO 371 | Thyroid Hormone Receptor
相關(guān)產(chǎn)品Propylthiouracil | Liothyronine | L-Thyroxine | L-Thyroxine sodium | 2,2-BIS(2-HYDROXY-5-BIPHENYLYL)PROPANE | Resmetirom | DS08210767 | Carbimazole | Methimazole | Liothyronine sodium | 2-Thiouracil | Tiratricol
相關(guān)庫經(jīng)典已知活性庫 | 藥物功能重定位化合物庫 | NO PAINS 化合物庫 | 內(nèi)分泌激素分子庫 | 已知活性化合物庫

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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