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Postion:Product Catalog >nAChR agonist 1
nAChR agonist 1
  • nAChR agonist 1

nAChR agonist 1 NEW

Price $86 $178 $273
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-18

Product Details

Product Name: nAChR agonist 1 CAS No.: 1394371-75-5
Purity: 97.59% Supply Ability: 10g
Release date: 2024/11/18

Product Introduction

Bioactivity

名稱nAChR agonist 1
描述nAChR agonist 1 (DUN71755) is a brain-permeable and orally efficacious positive allosteric α7 nicotinic acetylcholine receptor (α7 nAChR)modulator.
體內(nèi)活性nAChR agonist 1(compound 28) is a novel PAM of α7 nicotinic acetylcholine receptor (α7 nAChR).?Compound 28 showed good in vitro potency, with pharmacokinetic profile across species with excellent brain penetration and residence time.?Compound 28 robustly reversed the cognitive deficits in episodic/working memory in both time-delay and scopolamine-induced amnesia paradigms in the novel object and social recognition tasks, at very low dose levels.
存儲(chǔ)條件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度DMSO : 120 mg/mL (285.76 mM), Sonication is recommended.
關(guān)鍵字oral | Nicotinic acetylcholine receptors | neuroblastoma | nAChR agonist-1 | nAChR agonist1 | nAChR agonist 1 | nAChR | Inhibitor | inhibit | DUN-71755 | DUN 71755 | disease | deficits | cognitive | cells | brain-permeable | Alzheimer’s
相關(guān)產(chǎn)品Adiphenine hydrochloride | Nanofin | Forskolin | Pilocarpine Hydrochloride | (+)-Sparteine | Olanzapine | CLOZAPINE N-OXIDE | Pilocarpine nitrate | Ribavirin | Amitriptyline hydrochloride | Choline chloride | Propoxur
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Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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