Mometasone furoate NEW
| Price | $39 | $48 | $88 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Mometasone furoate | CAS No.: 83919-23-7 |
| Purity: 99.48% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Mometasone furoate |
| Description | Mometasone furoate (Sch32088) is a pregnadienediol derivative with anti-allergic and anti-inflammatory properties, used in the management of asthma and allergic rhinitis, as well as a topical treatment for skin disorders. |
| In vitro | Both 0.02% Mometasone furoate and 0.1% Fluticasone propionate significantly suppress the increase in antigen-induced nasal rubbing even six hours after topical application, demonstrating their lasting effects. Mometasone furoate reduces nasal rubbing in rats and, at the highest tested dose in mice (3mg/kg), inhibits the increased sensitivity to aerosolized acetylcholine. The compound dose-dependently suppresses the elevation of eosinophil counts in the bronchoalveolar lavage fluid and lung tissue of mice challenged with sensitizing ovalbumin. Furthermore, a dosage of 33 mg/kg Mometasone furoate lowers the percentage of CD44+ T helper cells (activated/memory cells) to levels observed in mice not challenged with sensitizing ovalbumin, indicating its immunomodulatory potential. |
| In vivo | Mometasone furoate effectively inhibits the production of cytokines, including interleukin (IL)-4, IL-5, and interferon-γ, in human CD4+ T cells stimulated by anti-CD3. It also efficiently suppresses the activation of Th cells, including type 2 helper T (Th2) cells, in draining lymph nodes, leading to the suppression of the IgE response. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 45 mg/mL (86.3 mM), Sonication is recommended. Ethanol : < 1 mg/mL (insoluble or slightly soluble) |
| Keywords | Inhibitor | eczema | hay fever | inhibit | skin corticosteroid | Anti-inflammatory | Mometasone furoate | Sch 32088 | Sch-32088 | Glucocorticoid Receptor | Mometasone Furoate | asthma | steroid |
| Inhibitors Related | Nimodipine | Hydrocortisone | Mifepristone | Prednisolone acetate | Cortisone | Dexamethasone acetate | Dexamethasone Phosphate disodium | Prednisone acetate | Desonide | Corticosterone |
| Related Compound Libraries | Bioactive Compound Library | EMA Approved Drug Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | FDA-Approved Drug Library | Anti-Cancer Approved Drug Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Anti-Metabolism Disease Compound Library | Anti-Cancer Drug Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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