Fluticasone furoate NEW
| Price | $30 | $48 | $84 |
| Package | 5mg | 10mg | 25mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Fluticasone furoate | CAS No.: 397864-44-7 |
| Purity: 99.58% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Fluticasone furoate |
| Description | Fluticasone furoate (Avamys) is a synthetic trifluorinated corticosteroid derived from fluticasone with a Kd of 0.3 nM. Fluticasone furoate has potent anti-inflammatory, anti-asthmatic activity, and low systemic exposure. Fluticasone furoate can be used as a nasal spray for studies about allergic rhinitis treatment. |
| In vitro | Fluticasone furoate displays great potency in inhibiting tumor necrosis factor synthesis and action. Fluticasone furoate prevents damage to cultured human lung epithelial cells by different stimuli[2]. |
| In vivo | Fluticasone furonate is excreted mainly in the feces, with only minor amounts in the urine. Fluticasone furonate is 99.4% bound to plasma protein in vitro. Clearance of Fluticasone furonate is primarily by hydrolysis in the liver by the cytochrome P450 isozyme CYP3A4 that converts the drug to the 17β-carboxylic acid metabolite, which displays low glucocorticoid receptor agonist potency[2]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | H2O : Insoluble DMSO : 95 mg/mL (176.39 mM), Sonication is recommended. |
| Keywords | Inhibitor | fluorinated | lipophilic | rhinitis | CYP3A4 | inhibit | intranasal | allergic | corticosteroid | Fluticasone Furoate | anti-asthmatic | Anti-inflamatory | Glucocorticoid Receptor |
| Inhibitors Related | Nimodipine | Hydrocortisone | Mifepristone | Prednisolone acetate | Cortisone | Dexamethasone acetate | Dexamethasone Phosphate disodium | Prednisone acetate | Desonide | Corticosterone |
| Related Compound Libraries | Nuclear Receptor Compound Library | Bioactive Compound Library | Pediatric Drug Library | EMA Approved Drug Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | Anti-Cancer Approved Drug Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Anti-Cancer Drug Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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