Isovaleramide NEW
| Price | $40 | $92 |
| Package | 100mg | 500mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-08 |
Product Details
| Product Name: Isovaleramide | CAS No.: 541-46-8 |
| Purity: 99.47% | Supply Ability: 10g |
| Release date: 2024/11/08 |
Product Introduction
Bioactivity
| 名稱 | Isovaleramide |
| 描述 | Isovaleramide (3-Methylbutanamide) is an anticonvulsant molecule isolated from Valeriana pavonii, which can inhibit the liver alcohol dehydrogenases. |
| 體外活性 | Research on the reproductive toxicity of Isovaleramide in mice, rats, and rabbits demonstrates its potential to be significantly lower than that of VPA. Oral administration of Isovaleramide at a dose of 100 mg/kg resulted in a 90% protection index against maximal electroshock seizures in mice. |
| 體內(nèi)活性 | At a concentration of 0.15%, Isovaleramide induces the formation of nitrile hydratase in Rhodococcus sp. YH 3-3. In in vitro assays, 300 μM Isovaleramide inhibits 42% of 3H-FNZ binding to its target site. At concentrations up to 1000 μM, Isovaleramide does not affect the binding and uptake assays of various neurotransmitters in vitro, suggesting that its mechanism of action does not involve direct receptor-mediated effects. |
| 存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | Ethanol : 16 mg/mL (158.2 mM) H2O : < 1 mg/mL (insoluble or slightly soluble) DMSO : 75 mg/mL (741.47 mM), Sonication is recommended. |
| 關鍵字 | inhibit | Inhibitor | Isovaleramide |
| 相關庫 | 抗癌天然產(chǎn)物庫 | 經(jīng)典已知活性庫 | ReFRAME 相關化合物庫 | 藥物功能重定位化合物庫 | 天然產(chǎn)物庫 | 煙草單體化合物庫 | NO PAINS 化合物庫 | 高通量篩選天然產(chǎn)物庫 | 臨床期小分子藥物庫 | 已知活性化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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TargetMol Chemicals Inc.
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2024-11-08 |
United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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