Glucagon (1-29), bovine, human, porcine hydrochloride NEW
| Price | $79 | $193 | $289 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Glucagon (1-29), bovine, human, porcine hydrochloride | CAS No.: 28270-04-4 |
| Purity: 98.03% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Glucagon (1-29), bovine, human, porcine hydrochloride |
| Description | Glucagon (1-29), bovine, human, porcine hydrochloride (Porcine glucagon hydrochloride) is a peptide hormone produced by pancreatic α-cells that activates HNF4α, increases HNF4α phosphorylation, and stimulates gluconeogenesis. |
| In vitro | Glucagon stimulates both hepatic kisspeptin1 production and gluconeogenesis. Upon binding to its receptor Gcgr, Glucagon activates cAMP-PKA signaling to stimulate hepatic glucose production (HGP) and cause hyperglycemia. Glucagon (100 nM) increases the phosphorylation of HNF4α. Glucagon (100 nM) represses CYP7A1 mRNA expression in human primary hepatocytes [3]. |
| In vivo | Glucagon (20 μg/kg) increases glycemia and does not stimulate insulin secretion in ambient-fed mice. High-dose (1 mg/kg) Glucagon lowers glycemia compared with PBS control and stimulates insulin secretion in ambient-fed mice [4]. |
| Storage | store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 10 mM H2O : 40 mg/mL (11.37 mM), Sonication is recommended. |
| Keywords | Porcine glucagon | peptide | hormone | gluconeogenesis | Inhibitor | pancreatic α | Glucagon (129), bovine, human, porcine hydrochloride | GCGR | inhibit | Glucagon Receptor | Glucagon Hydrochloride | HNF4α | HNF-4 | Glucagon (1-29), bovine, human, porcine | Porcine glucagon Hydrochloride | Glucagon , bovine, human, porcine Hydrochloride | Glucagon (1 29), bovine, human, porcine hydrochloride |
| Inhibitors Related | Hydrocortisone | Mifepristone | Corticosterone |
| Related Compound Libraries | Anti-Diabetic Compound Library | Peptide Compound Library | Endocrinology-Hormone Compound Library | NO PAINS Compound Library | Anti-Cancer Compound Library | Anti-Metabolism Disease Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $66.00/1mg |
VIP3Y
|
TargetMol Chemicals Inc.
|
2024-11-15 | |
| $65.00/1kg |
VIP2Y
|
Zibo Hangyu Biotechnology Development Co., Ltd
|
2023-11-30 | |
| $9.90/1kg |
VIP2Y
|
Wuhan Cell Pharmaceutical Co., Ltd
|
2023-04-07 |
United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
INQUIRY