Glucagon (1-29), bovine, human, porcine NEW
| Price | $66 | $198 |
| Package | 1mg | 5mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-15 |
Product Details
| Product Name: Glucagon (1-29), bovine, human, porcine | CAS No.: 16941-32-5 |
| Purity: 99.56% | Supply Ability: 10g |
| Release date: 2024/11/15 |
Product Introduction
Bioactivity
| 名稱 | Glucagon (1-29), bovine, human, porcine |
| 描述 | Glucagon (1-29), bovine, human, porcine is a hormone produced by pancreatic α-cells with glucagon activity, which promotes glycogenolysis and gluconeogenesis, and is used in the study of obesity and diabetes. |
| 體外活性 | Glucagon (1-29), bovine, human, porcine binds to its receptor Gcgr and activates the cAMP-PKA signaling pathway, which in turn promotes hepatic gluconeogenesis and triggers hyperglycemia. In addition, Glucagon (1-29), bovine, human, porcine stimulates hepatic production of kisspeptin1 and gluconeogenesis. [1] Glucagon (1-29), bovine, human, porcine inhibits the expression of CYP7A1 mRNA in human primary hepatocytes at a concentration of 100 nM and increases the phosphorylation of HNF4α. increased the phosphorylation level of HNF4α. [3] |
| 體內(nèi)活性 | A low dose of 20 μg/kg Glucagon (1-29), bovine, human, porcine increased blood glucose but did not stimulate insulin secretion in mice fed in a normal environment. A high dose of 1 mg/kg Glucagon (1-29), bovine, human, porcine lowered blood glucose and stimulated insulin secretion in mice fed in a normal environment compared to the PBS control. [4] |
| 存儲(chǔ)條件 | keep away from moisture,keep away from direct sunlight,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | DMSO : 1 mg/mL (0.29 mM), Sonication is recommended. H2O : 4 mg/mL (1.15 mM), Adjust pH to 2 with HCl and sonication is recommended.) |
| 關(guān)鍵字 | Porcine glucagon | Glucagon , bovine, human, porcine | Glucagon (129), bovine, human, porcine | Glucagon (1 29), bovine, human, porcine | Glucagon |
| 相關(guān)產(chǎn)品 | Tirzepatide Acetate(2023788-19-2 free base) | PF-06882961 Tris | L-168049 | PF-06882961 | Glucagon (1-29), bovine, human, porcine hydrochloride | (S, R)-LSN 3318839 | NNC 92-1687 | Adomeglivant | 6α-Methylprednisolone 21-hemisuccinate sodium salt | Orforglipron | LSN3318839 | HAEGTFT acetate(926018-95-3 free base) |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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