Compound 3344 hydrochloride NEW
Price | $146 | $298 | $448 |
Package | 1mg | 5mg | 10mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-19 |
Product Details
Product Name: Compound 3344 hydrochloride | Purity: 99.23% |
Supply Ability: 10g | Release date: 2024/11/19 |
Product Introduction
Bioactivity
Name | Compound 3344 hydrochloride |
Description | Compound 3344 hydrochloride is an inhibitor of KRAS-effector interactions,with an affnity of 126nM. |
In vitro | In vitro competition studies of 3344 hydrochloride binding to KRAS-G12V in waterLOGSY NMR show the anti-RAS scFv inhibits 3344 hydrochloride binding to KRAS. In view of the in vitro inhibition by the anti-RAS scFv of 3344 hydrochloride binding to RASand because the iDAb RAS interferes with BRET signal in cells, 3344 hydrochloride was used for validation of the BRET2 toolbox for RAS-effector PPI inhibitors. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 60 mg/ml (140.53 mM) |
Keywords | 2368246-78-8 free base | Compound 3344 Hydrochloride | 2368246-78-8 | Compound 3344 hydrochloride |
Inhibitors Related | Adagrasib | (S)-AMG-510 | BI-2493 | CCG-257081 | Ketoconazole | Deltarasin | MRTX1133 | Salirasib | RMC-6236 | (S)-(-)-Perillyl alcohol | CASIN | Sotorasib |
Related Compound Libraries | Anti-Colorectal Cancer Compound Library | Bioactive Compound Library | Pain-Related Compound Library | Membrane Protein-targeted Compound Library | Kinase Inhibitor Library | Anti-Cancer Metabolism Compound Library | Inhibitor Library | Bioactive Compounds Library Max | GPCR Compound Library | MAPK Inhibitor Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Address: 36?Washington?Street, Wellesley?Hills
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