Compound C108 NEW
Price | $38 | $82 | $132 |
Package | 1mg | 5mg | 10mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-01 |
Product Details
Product Name: Compound C108 | CAS No.: 15533-09-2 |
Purity: 99.77% | Supply Ability: 10g |
Release date: 2024/11/01 |
Product Introduction
Bioactivity
名稱 | Compound C108 |
描述 | Compound C108 is an inhibitor of GTPase-activating protein SH3 domain-binding protein 2 (G3BP2). Compound C108 can be used in studies about breast tumors and esophageal squamous cell carcinoma. |
體外活性 | In BT474 cells, Compound C108 (1 μM) shows anti-tumor activity[1]. In G3BP2 overexpressing KYSE410 cells and LINC01554 transfected KYSE30 cells, Compound C108 (4 μM) reduces the protein expression of G3BP2 and attenuates ESCC cell metastasis, migration and invasion[2]. |
體內(nèi)活性 | In a mouse xenograft model of breast cancer, compound C108 (1 μM) reduces the proportion of tumor-initiating cells approximately 10-fold[1]. |
存儲(chǔ)條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | DMF:PBS(pH 7.2)(1:6) : 0.14 mg/mL DMF : 1 mg/mL DMSO : 22.5 mg/mL (83.2 mM), Sonication is recommended. |
關(guān)鍵字 | Compound C-108 | Compound C 108 | Compound C108 |
相關(guān)產(chǎn)品 | RBC10 | Exo-1 | Tyrphostin 8 | Anti-inflammatory agent 49 | CID-4785700 | CCG 203769 | BQU57 | ML-097 | IMM-01 | NAV-2729 |
相關(guān)庫 | 經(jīng)典已知活性庫 | 膜蛋白靶向化合物庫 | 抑制劑庫 | 已知活性化合物庫 | GPCR靶點(diǎn)分子庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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