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Postion:Product Catalog >API>Synthetic Anti-infective Drugs>Antiseptics & Disinfectants Drugs>Cetrimonium bromide
Cetrimonium bromide
  • Cetrimonium bromide

Cetrimonium bromide NEW

Price $30 $39 $55
Package 50mg 100mg 200mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: Cetrimonium bromide CAS No.: 57-09-0
Purity: ≥95% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameCetrimonium bromide
DescriptionCetrimonium bromide (Lauroseptol) is is a mixture of different quaternary ammonium salts, which is a known component of the broad-spectrum antiseptic cetrimide.
In vitroIn a FaDu xenograft tumor model established in SCID mice, intraperitoneal administration of 5 mg/kg Cetrimonium Bromide daily for five consecutive days moderately inhibited tumor growth as compared to the vehicle treatment arm. Additionally, 5 μM of Cetrimonium Bromide effectively prevented tumor formation in FaDu cells within SCID mice.
In vivoCetrimonium Bromide exhibits a dose-dependent and radiation potentiating interaction that inhibits the clonogenic survival of FaDu cells. It induces nuclear pyknosis and bubbling in FaDu cells, consistent with the morphology of apoptotic nuclei, which is not observed in CTAB-treated GM05757 cells. Additionally, it reproducibly suppresses ATPase activity in FaDu cells, achieving approximately 90% inhibition at 50 μM. Cetrimonium Bromide reduces the cell viability in a variety of cell lines including FaDu, C666-1, UTSCC-8A, UTSCC-42A, MRC5, and GM05757 fibroblasts, with respective EC50 values of 2 μM, 3.8 μM, 3.5 μM, 4.2 μM, 11 μM, and 18 μM. It also diminishes the cell viability of A549 lung and MCF7 breast cancer cells with EC50 values of 17 μM and 12 μM, respectively.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 10 mg/mL (27.4 mM), Sonication is recommended.
Ethanol : 93 mg/mL (255.2 mM)
H2O : 100 mg/mL (274.4 mM)
KeywordsCetrimonium bromide | Inhibitor | Cetyltrimethylammonium | Hexadecyltrimethylammonium | Cetrimonium | inhibit | Cetrimonium Bromide
Inhibitors RelatedNeomycin sulfate | Rifampicin | Ampicillin sodium | Doxycycline (hyclate) | Kanamycin sulfate | G-418 disulfate | Sulfamethoxazole sodium | Metronidazole | Doxycycline | EDTA copper(II) disodium salt
Related Compound LibrariesFDA-Approved & Pharmacopeia Drug Library | Bioactive Compound Library | Approved Drug Library | Antibiotics Library | Drug Repurposing Compound Library | NO PAINS Compound Library | Cosmetic Ingredient Compound Library | Bioactive Compounds Library Max | Anti-Infection Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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