Cetrimonium bromide NEW
Price | $30 | $39 | $55 |
Package | 50mg | 100mg | 200mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-19 |
Product Details
Product Name: Cetrimonium bromide | CAS No.: 57-09-0 |
Purity: ≥95% | Supply Ability: 10g |
Release date: 2024/11/19 |
Product Introduction
Bioactivity
Name | Cetrimonium bromide |
Description | Cetrimonium bromide (Lauroseptol) is is a mixture of different quaternary ammonium salts, which is a known component of the broad-spectrum antiseptic cetrimide. |
In vitro | In a FaDu xenograft tumor model established in SCID mice, intraperitoneal administration of 5 mg/kg Cetrimonium Bromide daily for five consecutive days moderately inhibited tumor growth as compared to the vehicle treatment arm. Additionally, 5 μM of Cetrimonium Bromide effectively prevented tumor formation in FaDu cells within SCID mice. |
In vivo | Cetrimonium Bromide exhibits a dose-dependent and radiation potentiating interaction that inhibits the clonogenic survival of FaDu cells. It induces nuclear pyknosis and bubbling in FaDu cells, consistent with the morphology of apoptotic nuclei, which is not observed in CTAB-treated GM05757 cells. Additionally, it reproducibly suppresses ATPase activity in FaDu cells, achieving approximately 90% inhibition at 50 μM. Cetrimonium Bromide reduces the cell viability in a variety of cell lines including FaDu, C666-1, UTSCC-8A, UTSCC-42A, MRC5, and GM05757 fibroblasts, with respective EC50 values of 2 μM, 3.8 μM, 3.5 μM, 4.2 μM, 11 μM, and 18 μM. It also diminishes the cell viability of A549 lung and MCF7 breast cancer cells with EC50 values of 17 μM and 12 μM, respectively. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 10 mg/mL (27.4 mM), Sonication is recommended. Ethanol : 93 mg/mL (255.2 mM) H2O : 100 mg/mL (274.4 mM) |
Keywords | Cetrimonium bromide | Inhibitor | Cetyltrimethylammonium | Hexadecyltrimethylammonium | Cetrimonium | inhibit | Cetrimonium Bromide |
Inhibitors Related | Neomycin sulfate | Rifampicin | Ampicillin sodium | Doxycycline (hyclate) | Kanamycin sulfate | G-418 disulfate | Sulfamethoxazole sodium | Metronidazole | Doxycycline | EDTA copper(II) disodium salt |
Related Compound Libraries | FDA-Approved & Pharmacopeia Drug Library | Bioactive Compound Library | Approved Drug Library | Antibiotics Library | Drug Repurposing Compound Library | NO PAINS Compound Library | Cosmetic Ingredient Compound Library | Bioactive Compounds Library Max | Anti-Infection Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
Recommended supplier
Product name | Price | Suppliers | Update time | |
---|---|---|---|---|
$30.00/50mg |
VIP5Y
|
TargetMol Chemicals Inc.
|
2024-11-19 | |
$0.00/1KG |
VIP3Y
|
Hebei Weibang Biotechnology Co., Ltd
|
2024-11-01 | |
$10.00/25kg |
VIP6Y
|
Hebei Weibang Biotechnology Co., Ltd
|
2024-10-25 | |
$99.00/5kg |
VIP1Y
|
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
|
2024-08-19 | |
$3.50/1kg |
VIP1Y
|
Hebei Andu Technology Com.,Ltd
|
2024-08-17 | |
$120.00/1kg |
VIP3Y
|
Hebei Fengjia New Material Co., Ltd
|
2024-08-08 | |
$10.00/1kg |
VIP4Y
|
Hebei Chuanghai Biotechnology Co,.LTD
|
2024-08-08 | |
$6.00/1kg |
VIP1Y
|
HebeiShuoshengImportandExportco.,Ltd
|
2024-08-07 | |
$0.00/1kg |
VIP2Y
|
Hebei Kingfiner Technology Development Co.Ltd
|
2024-06-17 | |
$70.00/1kg |
VIP1Y
|
Hebei Zhuanglai Chemical Trading Co.,Ltd
|
2024-06-04 |
- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
INQUIRY