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Postion:Product Catalog >BCI hydrochloride
BCI hydrochloride
  • BCI hydrochloride

BCI hydrochloride NEW

Price $86
Package 2mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-20

Product Details

Product Name: BCI hydrochloride CAS No.: 95130-23-7
Purity: 99.95% Supply Ability: 10g
Release date: 2024/11/20

Product Introduction

Bioactivity

NameBCI hydrochloride
DescriptionBCI hydrochloride ((E)-BCI hydrochloride) is a selective dual-specificity phosphatase 6 (DUSP6) inhibitor that inhibits RANKL-mediated osteoclastogenesis and attenuates oophorectomy-induced bone loss.BCI hydrochloride has anti-inflammatory activity, reduces reactive oxygen species (ROS) production, and partially reverses AE-induced bone loss. BCI hydrochloride has anti-inflammatory activity and can reduce reactive oxygen species (ROS) production, partially reverse AE-induced cytotoxicity, and increase ERK activity, which can be used to study inflammatory diseases.
In vitroBCI hydrochloride (100 ng/mL; 24 hr) was able to down-regulate DUSP6 expression in RAW264.7 macrophages.BCI hydrochloride (0-1 nM; 24 hr) inhibited DUSP6 expression, as well as IL-1β and IL-6 production in lipopolysaccharide (LPS)-activated macrophages.BCI hydrochloride (0-4 nM; 24 hr), in turn reduced reactive oxygen species (ROS) production and activated the Nrf2 pathway in LPS-activated macrophages. [1][2]
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 10 mg/mL (28.26 mM), Sonication is recommended.
Inhibitors Relatedh-NTPDase-IN-2 | PTP1B-IN-22 | Disodium monofluorophosphate | β-Glycerophosphate disodium salt pentahydrate | MLS000544460 | Idoxuridine | Cyclosporine | Cis-5-Norbornene-exo-2,3-dicarboxylic Anhydride | CaMKP Inhibitor | SHP099 | L-Ascorbic acid 2-phosphate magnesium | Trimyristin

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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