ATI-2341 acetate(1337878-62-2 free base) NEW
Price | $79 | $270 | $398 |
Package | 1mg | 5mg | 10mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-04 |
Product Details
Product Name: ATI-2341 acetate(1337878-62-2 free base) | Purity: 97.14% |
Supply Ability: 10g | Release date: 2024/11/04 |
Product Introduction
Bioactivity
名稱 | ATI-2341 acetate(1337878-62-2 free base) |
描述 | ATI-2341 acetate is an effective allosteric agonist of CXCR4, it activates Gα1 instead of Gα13. ATI-2341 acetate activates inhibitory heterotrimeric G protein (GI) to promote the inhibition of cAMP production and induce calcium mobilization. |
體外活性 | ATI-2341 induced CXCR4- and G protein-dependent signaling, receptor internalization, and chemotaxis in CXCR4-expressing cells[1]. |
體內(nèi)活性 | ATI-2341 induced dose-dependent peritoneal recruitment of PMNs when administered i.p. to mice. When administered systemically by i.v. bolus, ATI-2341 acted as a functional antagonist and dose-dependently mediated release of PMNs from the bone marrow of both mice and cynomolgus monkeys[1]. |
存儲(chǔ)條件 | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | DMSO : Slightly soluble |
關(guān)鍵字 | ATI-2341 acetate(1337878-62-2 free base) | ATI2341 acetate(1337878622 free base) | ATI 2341 acetate(1337878 62 2 free base) |
相關(guān)產(chǎn)品 | Tannic acid | Nicotinamide N-oxide |
相關(guān)庫(kù) | 細(xì)胞因子抑制劑庫(kù) | 自噬庫(kù) | 趨化因子抑制劑庫(kù) | 多肽分子庫(kù) | NO PAINS 化合物庫(kù) |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
Recommended supplier
Product name | Price | Suppliers | Update time | |
---|---|---|---|---|
$76.00/1mg |
VIP3Y
|
TargetMol Chemicals Inc.
|
2024-10-28 | |
$0.00/1kg |
VIP5Y
|
Zison Pharmaceutical (Shandong) Co., Ltd.
|
2024-05-24 | |
$102.00/1kg |
VIP2Y
|
Wuhan Quanjinci New Material Co.,Ltd.
|
2023-10-24 |
- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
INQUIRY