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Postion:Product Catalog >(4E)-SUN9221
(4E)-SUN9221
  • (4E)-SUN9221

(4E)-SUN9221 NEW

Price $700 $1800
Package 1mg 5mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-07

Product Details

Product Name: (4E)-SUN9221 CAS No.: 222318-55-0
Purity: 97.79% Supply Ability: 10g
Release date: 2024/11/07

Product Introduction

Bioactivity

名稱(4E)-SUN9221
描述(4E)-SUN9221 is a potent dual α1-adrenergic receptor and 5-HT2 receptor antagonist, exhibiting antihypertensive and antiplatelet aggregation activities in hypertensive rats.
體外活性In human platelet-rich plasma (PRP), (4E)-SUN9221 potently inhibits collagen-, ADP-, and epinephrine-induced platelet aggregation, with IC50s of 10 nM, 35 nM, and 14 nM, respectively. Additionally, (4E)-SUN9221 displays potent α1-adrenergic antagonist activity (pA2 =8.89±0.21) and 5-HT2 antagonist activity (pA2 =8.74±0.22)[1].
體內(nèi)活性In conscious spontaneously hypertensive rats (SHR), (4E)-SUN9221 reduces blood pressure in a dose-dependent manner when administered orally at doses of 1, 3, and 10 mg/kg. Specifically, (4E)-SUN9221 at a dose of 3 mg/kg exhibits antihypertensive activity in SHR[1].
存儲(chǔ)條件store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
關(guān)鍵字SUN9221 | SUN-9221 | (4E)-SUN-9221 | SUN 9221 | (4E)SUN9221 | (4E) SUN9221
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Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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