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Postion:Product Catalog >API>Nervous system drugs>Cholinergic drugs>(-)-Huperzine A
(-)-Huperzine A
  • (-)-Huperzine A
  • (-)-Huperzine A
  • (-)-Huperzine A

(-)-Huperzine A NEW

Price $200 $150 $100
Package 1kg 100kg 1000kg
Min. Order: 1kg
Supply Ability: 3000kgs/month
Update Time: 2024-07-08
Related documents: COA

Product Details

Product Name: (-)-Huperzine A CAS No.: 102518-79-6
Min. Order: 1kg Purity: 99%
Supply Ability: 3000kgs/month Release date: 2024/07/08

(-)-Huperzine A (CAS: 102518-79-6)

Chemical Information

  • IUPAC Name: (1R,9R,13E)-1-Amino-13-ethylidene-11-methyl-7,11-diazatetracyclo[7.4.1.0^2,7.0^10,12]trideca-2(7),3,5-trien-8-one

  • Synonyms: Huperzine A, Selagine

  • Molecular Formula: C15H18N2O

  • Molecular Weight: 242.32 g/mol

Structure and Properties

  • Chemical Structure: Huperzine A is an alkaloid derived from the plant Huperzia serrata. It features a complex tetracyclic structure with a unique arrangement of nitrogen and oxygen atoms.

  • Appearance: Typically a white to off-white crystalline powder.

  • Solubility: Soluble in organic solvents such as ethanol and methanol; slightly soluble in water.

Biological Significance

  • Mechanism of Action: Huperzine A is a potent inhibitor of acetylcholinesterase (AChE), the enzyme that breaks down the neurotransmitter acetylcholine. By inhibiting AChE, huperzine A increases the levels of acetylcholine in the brain, which is beneficial for cognitive functions.

  • Therapeutic Uses:

    • Cognitive Enhancer: Used for its potential to improve memory and cognitive function, particularly in conditions like Alzheimer's disease and other forms of dementia.

    • Neuroprotective Effects: May offer protective benefits against neurodegenerative diseases due to its antioxidant properties and ability to protect neurons from glutamate-induced toxicity.

Applications and Uses

  • Medical and Dietary Supplement:

    • Available as an over-the-counter dietary supplement aimed at enhancing memory and cognitive functions.

    • Investigated in clinical trials for the treatment of Alzheimer's disease and other cognitive disorders.

  • Research: Extensively studied for its pharmacological effects on the nervous system and its potential therapeutic applications.

Safety and Handling

  • Dosage and Administration: Common dosages in supplements range from 50 to 200 micrograms per day. It is important to follow dosage recommendations to avoid potential side effects.

  • Side Effects: Generally well-tolerated, but possible side effects include nausea, diarrhea, vomiting, sweating, blurred vision, and cramping.

  • Precautions: Should be used with caution in individuals with cardiovascular diseases or those taking medications that affect heart rate and rhythm.

References and Resources

Huperzine A is significant in both clinical and research contexts due to its potential cognitive-enhancing and neuroprotective properties. For precise safety guidelines and detailed information, always refer to the specific Material Safety Data Sheet (MSDS) provided by the manufacturer or supplier.


Company Profile Introduction

SACH BIOTECH Co.,Ltd. was reorganized and established in 2023, formerly known as Hangzhou Shitai Biotech Co.,Ltd. The main body of the company is located by the beautiful West Lake of Hangzhou. The main production base is located in Shandong Province, China, and the pilot production base and laboratory are located in Henan province. After 15 years of hard work and accumulation, we now have a strong research and development team and experimental equipment, and the pilot plant can meet the requirements of different customers. The production base located in Shandong, China can meet the needs of customers for industrial scale production.

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  • Since: 2023-06-25
  • Address: 2-513, No. 364, Tongyun Street, Liangzhu Street, Yuhang District, Hangzhou, Zhejiang China
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