- Fotemustine USP/EP/BP
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- $1.10 / 1g
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2021-07-06
- CAS:92118-27-9
- Min. Order: 1g
- Purity: 99.9%
- Supply Ability: 100 Tons Min
- Fotemustine
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- $1.00 / 1KG
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2020-02-19
- CAS:92118-27-9
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 200kgs
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| | Fotemustine Basic information |
| Product Name: | Fotemustine | | Synonyms: | 1-(2-chloroethyl)-3-(1-diethoxyphosphorylethyl)-1-nitrosourea;FOTEMUSTINE;Fotemustin;Muphoran;S-10036;Phosphonic acid, P-[1-[[[(2-chloroethyl)nitrosoamino]carbonyl]amino]ethyl]-, diethyl ester;[1-[[[(2-Chloroethyl)nitlx~amino]carbonyl]amino]ethyl]phosphonic acid diethyl ester;[1-[[[(2-Chloroethyl)nitrosoamino]carbonyl]amino]ethyl]phosphonic acid diethyl ester | | CAS: | 92118-27-9 | | MF: | C9H19ClN3O5P | | MW: | 315.69 | | EINECS: | | | Product Categories: | | | Mol File: | 92118-27-9.mol |  |
| | Fotemustine Chemical Properties |
| Melting point | 85° | | density | 1.37±0.1 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | H2O: ≥1mg/mL | | form | powder | | pka | 9.47±0.46(Predicted) | | color | light yellow | | CAS DataBase Reference | 92118-27-9(CAS DataBase Reference) |
| | Fotemustine Usage And Synthesis |
| Description | Fotemustine is a new nitrosourea reportedly effective in the treatment of disseminated
malignant melanoma, with only mild hematological toxicity. Response rate is generally
lower in patients with colonic, breast, head and neck cancer. | | Originator | Servier (France) | | Uses | Fotemustine is used in patients malignant gliomas to improve the efficacy of radiotherapy. Used in the treatment of glioblastomas. | | Definition | ChEBI: Diethyl (1-{[(2-chloroethyl)(nitroso)carbamoyl]amino}ethyl)phosphonate is a member of the class of N-nitrosoureas that is ethyl diethylphosphonate in the hydrogen at position 1 of the ethyl group attached to the phosphorus has been replaced by a [(2-chloroethyl)(nitroso)carbamoyl]amino group. It is an organic phosphonate, a member of N-nitrosoureas and an organochlorine compound. | | Brand name | Muphoran |
| | Fotemustine Preparation Products And Raw materials |
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