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ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >PI3K / Akt / mTOR >S6 Kinase Inhibitors >LY2584702

LY2584702

LY2584702 Suppliers list
Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +undefined-21-51877795
Email: ivan@atkchemical.com
Products Intro: Product Name:LY-2584702
CAS:1082949-67-4
Purity:98% Package:10MG;50MG;100MG,1G,5G,10G.100G
Company Name: Hubei Jusheng Technology Co.,Ltd.
Tel: 18871490254
Email: linda@hubeijusheng.com
Products Intro: Product Name:LY2584702
CAS:1082949-67-4
Purity:0.99 Package:5KG;1KG
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:LY-2584702 free base
CAS:1082949-67-4
Purity:98.72% Package:5mg;70USD|10mg;90USD|25mg;198USD Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Dideu Industries Group Limited
Tel: +86-29-89586680 +86-15129568250
Email: 1026@dideu.com
Products Intro: Product Name:LY2584702
CAS:1082949-67-4
Purity:99.9% Package:25kgs/Drum;200kgs/Drum Remarks:FDA GMP CEP Approved Manufacturer
Company Name: InvivoChem
Tel: +1-708-310-1919 +1-13798911105
Email: sales@invivochem.cn
Products Intro: Product Name:LY2584702
CAS:1082949-67-4
Purity:98% Package:50mg Remarks:V0240

LY2584702 manufacturers

  • LY-2584702 free base
  • LY-2584702 free base pictures
  • $39.00 / 1mg
  • 2024-11-19
  • CAS:1082949-67-4
  • Min. Order:
  • Purity: 98.72%
  • Supply Ability: 10g
LY2584702 Basic information
Product Name:LY2584702
Synonyms:LY2584702;LY-2584702 (free base);LY2584702 TsOH;4-[4-[4-[4-fluoro-3-(trifluoromethyl)phenyl]-1-methyl-imidazol-2-yl]-1-piperidyl]-1H-pyrazolo[3,4-d]pyrimidine LY2584702;4-[4-[4-[4-Fluoro-3-(trifluoromethyl)phenyl]-1-methyl-1H-imidazol-2-yl]-1-piperidinyl]-1H-pyrazolo[3,4-d]pyrimidine;4-[4-[4-[4-Fluoro-3-(trifluoromethyl)phenyl]-1-methylimidazol-2-yl]piperidin-1-yl]-1H-pyrazolo;LY2584702 USP/EP/BP;1H-Pyrazolo[3,4-d]pyrimidine, 4-[4-[4-[4-fluoro-3-(trifluoromethyl)phenyl]-1-methyl-1H-imidazol-2-yl]-1-piperidinyl]-
CAS:1082949-67-4
MF:C21H19F4N7
MW:445.42
EINECS:
Product Categories:Inhibitors
Mol File:1082949-67-4.mol
LY2584702 Structure
LY2584702 Chemical Properties
storage temp. RT (des.)
solubility Soluble in DMSO (up to 1 mg/ml) or in DMF (up to 3 mg/ml).
form solid
color Yellow
Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20° for up to 3 months.
Safety Information
HS Code 2933998090
MSDS Information
LY2584702 Usage And Synthesis
DescriptionLYS6K2 (1082949-67-4) is a selective inhibitor of the p70 ribosomal S6 kinase (S6K).1 Blocks the phosphorylation of S6 at concentrations as low as 0.1-0.3 μM with no activity at GSK3β and Erk1/2 at 10 μM.2?LYS6K2 is a useful tool to dissect insulin receptor signaling pathways and was employed to show that the action of mTORC1 on SREB P-1c expression is not mediated by S6K.2?Cell permeable.
UsesLY 2584702 is an orally available inhibitor of p70S6K signalling and potential antineoplastic activity. Used in combination with Erlotinib or Everolimus as an anti-tumor treatment.
References1) Fenton et al. (2011), Functions and regulation of the 70kDa ribosomal S6 kinases; Int. J. Biochem. Cell Biol., 43 47 2) Li et al. (2010), Bifurcation of insulin signaling pathway in the rat liver: mTORC1 required for stimulation of lipogenesis, but no inhibition of gluconeogenesis; Proc. Natl. Acad. Sci. USA 107 3441
LY2584702 Preparation Products And Raw materials
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