Company Name: |
TargetMol Chemicals Inc.
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Tel: |
15002134094 |
Email: |
marketing@targetmol.cn |
Products Intro: |
Product Name:IS-741 sodium monohydrate CAS:351999-87-6 Package:100mg/RMB 17500;25mg/RMB 10600;50mg/RMB 13800
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Cyclohexanecarboxamide, N-[2-[(ethylsulfonyl)amino]-5-(trifluoromethyl)-3-pyridinyl]-, sodium salt, hydrate (1:1:1) manufacturers
- Fuzapladib sodium
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- $0.00 / 1kg
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2024-02-27
- CAS:351999-87-6
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 100 tons
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| Cyclohexanecarboxamide, N-[2-[(ethylsulfonyl)amino]-5-(trifluoromethyl)-3-pyridinyl]-, sodium salt, hydrate (1:1:1) Basic information |
| Cyclohexanecarboxamide, N-[2-[(ethylsulfonyl)amino]-5-(trifluoromethyl)-3-pyridinyl]-, sodium salt, hydrate (1:1:1) Chemical Properties |
InChI | InChI=1S/C15H20F3N3O3S.Na.H2O.H/c1-2-25(23,24)21-13-12(8-11(9-19-13)15(16,17)18)20-14(22)10-6-4-3-5-7-10;;;/h8-10H,2-7H2,1H3,(H,19,21)(H,20,22);;1H2; | InChIKey | QGYVDECYMSBHMK-UHFFFAOYSA-N | SMILES | N(C1C=C(C(F)(F)F)C=NC=1NS(=O)(=O)CC)C(C1CCCCC1)=O.[NaH].O |
| Cyclohexanecarboxamide, N-[2-[(ethylsulfonyl)amino]-5-(trifluoromethyl)-3-pyridinyl]-, sodium salt, hydrate (1:1:1) Usage And Synthesis |
Description | Fuzapladib sodium hydrate, also known as N-[2-(Sodioethanesulfonamido)-5-(trifluoromethyl)pyridin-3-yl]cyclohexanecarboxamide monohydrate, is a phospholipase A2 ( PLA2) inhibitor and a leukocyte function-associated antigen-1 (LFA-1) activation inhibitor for the treatment of acute pancreatitis (AP) in animal species (dogs). | Uses | Fuzapladib Sodium Hydrate is a synthetic anti-inflammatory agent that shows inhibitory effect on cytosolic phospholipase A2 (cPLA2). | Mechanism of action | Fuzapladib sodium hydrate controls the progression of pancreatitis by blocking the activation of adhesion molecules (integrins) expressed on the surface of inflammatory cells and preventing inflammatory cells from adhering to vascular endothelial cells and infiltrating tissues. |
| Cyclohexanecarboxamide, N-[2-[(ethylsulfonyl)amino]-5-(trifluoromethyl)-3-pyridinyl]-, sodium salt, hydrate (1:1:1) Preparation Products And Raw materials |
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