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ChemicalBook >> CAS DataBase List >> Trifluridine

Trifluridine

Trifluridine price.
  • $32 - $1899.98
  • Product name: Trifluridine
  • CAS: 70-00-8
  • MF: C10H11F3N2O5
  • MW: 296.2
  • EINECS:200-722-8
  • MDL Number:MFCD00006534
  • Synonyms:5-TRIFLUORO THYMIDINE;2''-DEOXY-5-(TRIFLUOROMETHYL)URIDINE (TRIFLUOROTHYMIDINE);2’-deoxy-5-(trifluoromethyl)-uridin ;5-(trifluoromethyl)deoxyuridine ;5-trifluoro-2’-deoxythymidine ;alpha,alpha,alpha-trifluoro-thymidin ;f3dthd ;5-TRIFLUOROTHYMIDINE extrapure (Trifluridine)
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Brand
  • Abosyn
  • AHH
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Apolloscientific
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • Chem-Impex
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • SynQuest Laboratories
  • TCI Chemical
  • Tocris
  • TRC
  • Usbiological
Package
  • 10mM(in 1mL DMSO)
  • 25mg
  • 50mg
  • 50
  • 100mg
  • 200mg
  • 250mg
  • 0.25g
  • 500mg
  • 1g
  • 2g
  • 5g
  • ManufacturerAbosyn
  • Product number61-0886
  • Product description1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-(trifluoromethyl)pyrimidine-2,4(1H,3H)-dione 95-98%
  • Packaging0.25g
  • Price$180
  • Updated2021-12-16
  • Buy
  • ManufacturerAHH
  • Product numberMT-59894
  • Product descriptionTrifluridine 98%
  • Packaging5g
  • Price$880
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ10508
  • Product descriptionTrifluridine
  • Packaging25mg
  • Price$49
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberK179
  • Product descriptionTrifluridine
  • Packaging100mg
  • Price$54
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ99711
  • Product descriptionTrifluridine
  • Packaging250mg
  • Price$65
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA179915
  • Product description1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-(trifluoromethyl)pyrimidine-2,4(1H,3H)-dione 98+%
  • Packaging50mg
  • Price$32
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA179915
  • Product description1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-(trifluoromethyl)pyrimidine-2,4(1H,3H)-dione 98+%
  • Packaging100mg
  • Price$51
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA179915
  • Product description1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-(trifluoromethyl)pyrimidine-2,4(1H,3H)-dione 98+%
  • Packaging250mg
  • Price$94
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA179915
  • Product description1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-(trifluoromethyl)pyrimidine-2,4(1H,3H)-dione 98+%
  • Packaging1g
  • Price$237
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA179915
  • Product description1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-(trifluoromethyl)pyrimidine-2,4(1H,3H)-dione 98+%
  • Packaging5g
  • Price$698
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberNUC0000876
  • Product description5-TRIFLUORO THYMIDINE 95.00%
  • Packaging25MG
  • Price$150.15
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberNUC0000876
  • Product description5-TRIFLUORO THYMIDINE 95.00%
  • Packaging50MG
  • Price$224.7
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberNUC0000876
  • Product description5-TRIFLUORO THYMIDINE 95.00%
  • Packaging1G
  • Price$860.48
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberNUC0000876
  • Product description5-TRIFLUORO THYMIDINE 95.00%
  • Packaging5G
  • Price$1899.98
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8542
  • Product descriptionTriflurdine(Viroptic)
  • Packaging50mg
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8542
  • Product descriptionTriflurdine(Viroptic)
  • Packaging10mM(in 1mL DMSO)
  • Price$75
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Abosyn 61-0886 1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-(trifluoromethyl)pyrimidine-2,4(1H,3H)-dione 95-98% 0.25g $180 2021-12-16 Buy
AHH MT-59894 Trifluridine 98% 5g $880 2021-12-16 Buy
AK Scientific J10508 Trifluridine 25mg $49 2021-12-16 Buy
AK Scientific K179 Trifluridine 100mg $54 2021-12-16 Buy
AK Scientific J99711 Trifluridine 250mg $65 2021-12-16 Buy
Ambeed A179915 1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-(trifluoromethyl)pyrimidine-2,4(1H,3H)-dione 98+% 50mg $32 2021-12-16 Buy
Ambeed A179915 1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-(trifluoromethyl)pyrimidine-2,4(1H,3H)-dione 98+% 100mg $51 2021-12-16 Buy
Ambeed A179915 1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-(trifluoromethyl)pyrimidine-2,4(1H,3H)-dione 98+% 250mg $94 2021-12-16 Buy
Ambeed A179915 1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-(trifluoromethyl)pyrimidine-2,4(1H,3H)-dione 98+% 1g $237 2021-12-16 Buy
Ambeed A179915 1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-(trifluoromethyl)pyrimidine-2,4(1H,3H)-dione 98+% 5g $698 2021-12-16 Buy
American Custom Chemicals Corporation NUC0000876 5-TRIFLUORO THYMIDINE 95.00% 25MG $150.15 2021-12-16 Buy
American Custom Chemicals Corporation NUC0000876 5-TRIFLUORO THYMIDINE 95.00% 50MG $224.7 2021-12-16 Buy
American Custom Chemicals Corporation NUC0000876 5-TRIFLUORO THYMIDINE 95.00% 1G $860.48 2021-12-16 Buy
American Custom Chemicals Corporation NUC0000876 5-TRIFLUORO THYMIDINE 95.00% 5G $1899.98 2021-12-16 Buy
ApexBio Technology A8542 Triflurdine(Viroptic) 50mg $70 2021-12-16 Buy
ApexBio Technology A8542 Triflurdine(Viroptic) 10mM(in 1mL DMSO) $75 2021-12-16 Buy

Properties

Melting point :190-193 °C (lit.)
Density :1.4365 (estimate)
refractive index :50 ° (C=1, H2O)
storage temp. :2-8°C
solubility :Soluble in DMSO (up to 25 mg/ml) or in Water (up to 14 mg/ml)
form :solid
pka :pKa 7.85 (Uncertain)
color :Off-white
Merck :14,9687
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 1 month.
CAS DataBase Reference :70-00-8(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H341 Suspected of causing genetic defects Germ cell mutagenicity Category 2 Warning P201,P202, P281, P308+P313, P405,P501
H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Trifluridine (trifluorothymidine, TFT), a fluorinated pyrimidine nucleoside, is an anti-herpesvirus agent and an antitumor antimetabolite agent. It is an analog of thymidine which inhibits thymidylate synthase possesses antiviral and anticancer activity. After phosphorylation by thymidine kinase, it is incorporated into DNA where it induces DNA-damage and interferes with repair enzymes. Enhances frame shift insertion and deletion in CRISPR genome editing in pluripotent stem cells.

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