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ChemicalBook >> CAS DataBase List >> TG003

TG003

TG003 price.
  • $180 - $891
  • Product name: TG003
  • CAS: 719277-26-6
  • MF: C13H15NO2S
  • MW: 249.33
  • EINECS:
  • MDL Number:MFCD00624584
  • Synonyms:TG003;(Z)-1-(3-ETHYL-5-METHOXY-2, 3-DIHYDROBENZOTHIAZOL-2-YLIDENE) PROPAN-2-ONE;2-Propanone, 1-(3-ethyl-5-Methoxy-2(3H)-benzothiazolylidene)-, (1Z)-;(1Z)-1-(3-Ethyl-5-methoxy-2(3H)-benzothiazolylidene)-2-propanone;TG003(Z)
11 prices
Selected condition:
Brand
  • aablocks
  • Axon Medchem
  • ChemScene
  • Crysdot
  • Tocris
  • TRC
  • Usbiological
Package
  • 10
  • 25mg
  • 10mg
  • 50
  • 50mg
  • 100mg
  • Manufactureraablocks
  • Product numberAA0061D2
  • Product descriptionTg-003 99%
  • Packaging10mg
  • Price$235
  • Updated2021-12-16
  • Buy
  • Manufactureraablocks
  • Product numberAA0061D2
  • Product descriptionTg-003 99%
  • Packaging100mg
  • Price$769
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon1765
  • Product descriptionTG003 98%
  • Packaging50mg
  • Price$456.5
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-2036
  • Product descriptionTG003 99.54%
  • Packaging10mg
  • Price$180
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-2036
  • Product descriptionTG003 99.54%
  • Packaging50mg
  • Price$540
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-2036
  • Product descriptionTG003 99.54%
  • Packaging100mg
  • Price$660
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31000978
  • Product descriptionTG-003 95+%
  • Packaging25mg
  • Price$225
  • Updated2021-12-16
  • Buy
  • ManufacturerTocris
  • Product number4336
  • Product descriptionTG003 ≥98%(HPLC)
  • Packaging10
  • Price$212
  • Updated2021-12-16
  • Buy
  • ManufacturerTocris
  • Product number4336
  • Product descriptionTG003 ≥98%(HPLC)
  • Packaging50
  • Price$891
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberT337700
  • Product descriptionTG003
  • Packaging25mg
  • Price$410
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number256914
  • Product descriptionTG 003
  • Packaging10mg
  • Price$466
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA0061D2 Tg-003 99% 10mg $235 2021-12-16 Buy
aablocks AA0061D2 Tg-003 99% 100mg $769 2021-12-16 Buy
Axon Medchem Axon1765 TG003 98% 50mg $456.5 2021-12-16 Buy
ChemScene CS-2036 TG003 99.54% 10mg $180 2021-12-16 Buy
ChemScene CS-2036 TG003 99.54% 50mg $540 2021-12-16 Buy
ChemScene CS-2036 TG003 99.54% 100mg $660 2021-12-16 Buy
Crysdot CD31000978 TG-003 95+% 25mg $225 2021-12-16 Buy
Tocris 4336 TG003 ≥98%(HPLC) 10 $212 2021-12-16 Buy
Tocris 4336 TG003 ≥98%(HPLC) 50 $891 2021-12-16 Buy
TRC T337700 TG003 25mg $410 2021-12-16 Buy
Usbiological 256914 TG 003 10mg $466 2021-12-16 Buy

Properties

Melting point :132-132.5 °C
Boiling point :386.0±42.0 °C(Predicted)
Density :1.237±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: 33 mg/mL
form :solid
pka :-1.54±0.20(Predicted)
color :pale yellow
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

TG003 (719277-26-6) is a potent, ATP-competitive inhibitor of Clk-family kinases (IC50‘s = 15, 20 and 200 nM for mClk4, 1 and 2 respectively and >10 μM for mClk3).1?Also inhibits DYRK1A/B (IC50‘s = 24 and 34 nM respectively).2 Suppresses serine/arginine-rich protein phosphorylation, dissociation of nuclear speckles and Clk1/Sty-dependent alternative splicing in mammalian cells.1?TG003 affects the regulation of alternative splicing by phosphorylation of SR protein both in vitro and in vivo. Promotes skipping of exon 31 in the endogenous dystrophin gene.3 TG003 increases levels of Clk1/4 mature mRNAs by promoting splicing of the intron-retaining RNAs.4

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