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ChemicalBook >> CAS DataBase List >> Saracatinib

Saracatinib

Saracatinib price.
  • $28 - $1920
  • Product name: Saracatinib
  • CAS: 379231-04-6
  • MF: C27H32ClN5O5
  • MW: 542.03
  • EINECS:1592732-453-0
  • MDL Number:MFCD09832698
  • Synonyms:7-[2-[4-Methylpiperazin-1-yl]ethoxy]-5-[[tetrahydropyran-4-yl]oxy]-4-[[6-chloro-2,3-Methylenedioxyphenyl]aMino]quinazoline;(S)-2-(4-(4-chlorophenyl)-2,3,9-triMethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-N-(4-hydroxyphenyl)acetaMide;N-(5-Chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methyl-1-piperazinyl)ethoxy]-5-[(tetrahydro-2H-pyran-4-yl)oxy]-4-quinazolinamine Saracatinib (AZD0530);Saracatinib N-(5-Chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methyl-1-piperazinyl)ethoxy]-5-[(tetrahydro-2H-pyran-4-yl)oxy]-4-quinazolinamine;Saracatinib, >=98%;Gemcabene Calcium;saracatinib;N-(5-Chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methyl-1-piperazinyl)ethoxy]-5-[(tetrahydro-2H-pyran-4-yl)oxy]-4-quinazolinamine
41 prices
Selected condition:
Brand
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Axon Medchem
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Tocris
  • TRC
  • Usbiological
Package
  • 1unit
  • 5mg
  • 10mg
  • 25mg
  • 100mg
  • 200mg
  • 50mg
  • 50
  • 500mg
  • 10mM(in 1mL DMSO)
  • 250mg
  • 1g
  • 1000mg
  • 2g
  • ManufacturerApexBio Technology
  • Product numberA2133
  • Product descriptionSaracatinib(AZD0530)
  • Packaging1unit
  • Price$28
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA2133
  • Product descriptionSaracatinib(AZD0530)
  • Packaging5mg
  • Price$40
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA2133
  • Product descriptionSaracatinib(AZD0530)
  • Packaging10mM(in 1mL DMSO)
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA2133
  • Product descriptionSaracatinib(AZD0530)
  • Packaging25mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA2133
  • Product descriptionSaracatinib(AZD0530)
  • Packaging100mg
  • Price$260
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN60031
  • Product descriptionSaracatinib(AZD0530) ≥98%
  • Packaging10mg
  • Price$148
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2646
  • Product descriptionSaracatinib
  • Packaging10mg
  • Price$45
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2646
  • Product descriptionSaracatinib
  • Packaging25mg
  • Price$85
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2646
  • Product descriptionSaracatinib
  • Packaging100mg
  • Price$235
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2646
  • Product descriptionSaracatinib
  • Packaging250mg
  • Price$435
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2646
  • Product descriptionSaracatinib
  • Packaging1g
  • Price$975
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon3284
  • Product descriptionSaracatinib-AZD0530 99%
  • Packaging10mg
  • Price$77
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181121
  • Product descriptionSaracatinib (AZD0530) >98%
  • Packaging100mg
  • Price$510
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181121
  • Product descriptionSaracatinib (AZD0530) >98%
  • Packaging250mg
  • Price$615.4
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181121
  • Product descriptionSaracatinib (AZD0530) >98%
  • Packaging1000mg
  • Price$1208.7
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFS27794
  • Product descriptionSaracatinib
  • Packaging10mg
  • Price$85
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
ApexBio Technology A2133 Saracatinib(AZD0530) 1unit $28 2021-12-16 Buy
ApexBio Technology A2133 Saracatinib(AZD0530) 5mg $40 2021-12-16 Buy
ApexBio Technology A2133 Saracatinib(AZD0530) 10mM(in 1mL DMSO) $60 2021-12-16 Buy
ApexBio Technology A2133 Saracatinib(AZD0530) 25mg $100 2021-12-16 Buy
ApexBio Technology A2133 Saracatinib(AZD0530) 100mg $260 2021-12-16 Buy
Arctom CFN60031 Saracatinib(AZD0530) ≥98% 10mg $148 2021-12-16 Buy
AvaChem 2646 Saracatinib 10mg $45 2021-12-16 Buy
AvaChem 2646 Saracatinib 25mg $85 2021-12-16 Buy
AvaChem 2646 Saracatinib 100mg $235 2021-12-16 Buy
AvaChem 2646 Saracatinib 250mg $435 2021-12-16 Buy
AvaChem 2646 Saracatinib 1g $975 2021-12-16 Buy
Axon Medchem Axon3284 Saracatinib-AZD0530 99% 10mg $77 2021-12-16 Buy
Biorbyt Ltd orb181121 Saracatinib (AZD0530) >98% 100mg $510 2021-12-16 Buy
Biorbyt Ltd orb181121 Saracatinib (AZD0530) >98% 250mg $615.4 2021-12-16 Buy
Biorbyt Ltd orb181121 Saracatinib (AZD0530) >98% 1000mg $1208.7 2021-12-16 Buy
Biosynth Carbosynth FS27794 Saracatinib 10mg $85 2021-12-16 Buy

Properties

Melting point :84-89°C
Boiling point :671.2±55.0 °C(Predicted)
Density :1.348
storage temp. :-20°C
solubility :Soluble in DMSO (50 mg/ml) and ethanol (54 mg/mL with warming)
form :solid
pka :7.55±0.10(Predicted)
color :White
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Saracatinib is a dual inhibitor of the tyrosine kinases c-Src and Abl (IC50 = 2.7 and 30 nM, respectively). It less effectively inhibits other receptor and non-receptor tyrosine kinases as well as assorted serine/threonine kinases. Saracatinib is orally available and blocks cell motility, migration, adhesion, invasion, proliferation, differentiation, and survival. Through its effects on c-Src, it reduces osteoclast bone resorption. Saracatinib also blocks denque virus RNA replication through its effect on Fyn kinase.

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