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ChemicalBook >> CAS DataBase List >> Protocatechuic acid

Protocatechuic acid

Protocatechuic acid price.
  • $10 - $700
  • Product name: Protocatechuic acid
  • CAS: 99-50-3
  • MF: C7H6O4
  • MW: 154.12
  • EINECS:202-760-0
  • MDL Number:MFCD00002509
  • Synonyms:3,4-Dihydroxybenzoic acid >=97.0% (T);Carbohydroquinonic acid;Hypogallic acid;3,4-Dihydroxybenzoic acid, >=99%;Benzoic acid, 3,4-dihydroxy-;PROTOCATECHUIC ACID(RG);3,4-DIHYDROXYBENZOIC ACID / PROTOCATECHUIC ACID;4-Carboxy-1,2-dihydroxybenzene
46 prices
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Brand
  • AK Scientific
  • Alfa Aesar
  • ApexBio Technology
  • Apolloscientific
  • Arctom
  • AvaChem
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • Crysdot
  • DC Chemicals
  • Frontier Specialty Chemicals
  • JR MediChem
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • SynQuest Laboratories
  • TCI Chemical
  • TRC
  • Usbiological
Package
  • 10mM(in 1mL DMSO)
  • 5mg
  • 20mg
  • 50mg
  • 100MG
  • 200mg
  • 1000mg
  • 1g
  • 5g
  • 25g
  • 50g
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  • 250g
  • 500g
  • 1000g
  • 1kg
  • 2Kg
  • ManufacturerAK Scientific
  • Product numberJ91727
  • Product description3,4-Dihydroxybenzoic Acid
  • Packaging5g
  • Price$10
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberB24016
  • Product description3,4-Dihydroxybenzoic acid, 97%
  • Packaging25g
  • Price$61.5
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberB24016
  • Product description3,4-Dihydroxybenzoic acid, 97%
  • Packaging100g
  • Price$176
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberB24016
  • Product description3,4-Dihydroxybenzoic acid, 97%
  • Packaging500g
  • Price$570.65
  • Updated2024-03-01
  • Buy
  • ManufacturerApexBio Technology
  • Product numberN2466
  • Product description3,4-Dihydroxybenzoic Acid
  • Packaging200mg
  • Price$42
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberN2466
  • Product description3,4-Dihydroxybenzoic Acid
  • Packaging10mM(in 1mL DMSO)
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberN2466
  • Product description3,4-Dihydroxybenzoic Acid
  • Packaging1g
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberOR52125
  • Product description3,4-Dihydroxybenzoic Acid
  • Packaging25g
  • Price$57
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberOR52125
  • Product description3,4-Dihydroxybenzoic Acid
  • Packaging100g
  • Price$96
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberOR52125
  • Product description3,4-Dihydroxybenzoic Acid
  • Packaging500g
  • Price$360
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN97568
  • Product description3,4-Dihydroxybenzoic Acid
  • Packaging20mg
  • Price$30
  • Updated2021-12-16
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  • ManufacturerAvaChem
  • Product number3289
  • Product descriptionProtocatechuic Acid
  • Packaging5mg
  • Price$59
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number3289
  • Product descriptionProtocatechuic Acid
  • Packaging20mg
  • Price$119
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb594219
  • Product descriptionProtocatechuic Acid
  • Packaging20mg
  • Price$153
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb594219
  • Product descriptionProtocatechuic Acid
  • Packaging1000mg
  • Price$221
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb105706
  • Product description3,4-Dihydroxybenzoic acid >98%,Standard References Grade
  • Packaging20mg
  • Price$569.5
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific J91727 3,4-Dihydroxybenzoic Acid 5g $10 2021-12-16 Buy
Alfa Aesar B24016 3,4-Dihydroxybenzoic acid, 97% 25g $61.5 2024-03-01 Buy
Alfa Aesar B24016 3,4-Dihydroxybenzoic acid, 97% 100g $176 2024-03-01 Buy
Alfa Aesar B24016 3,4-Dihydroxybenzoic acid, 97% 500g $570.65 2024-03-01 Buy
ApexBio Technology N2466 3,4-Dihydroxybenzoic Acid 200mg $42 2021-12-16 Buy
ApexBio Technology N2466 3,4-Dihydroxybenzoic Acid 10mM(in 1mL DMSO) $50 2021-12-16 Buy
ApexBio Technology N2466 3,4-Dihydroxybenzoic Acid 1g $60 2021-12-16 Buy
Apolloscientific OR52125 3,4-Dihydroxybenzoic Acid 25g $57 2021-12-16 Buy
Apolloscientific OR52125 3,4-Dihydroxybenzoic Acid 100g $96 2021-12-16 Buy
Apolloscientific OR52125 3,4-Dihydroxybenzoic Acid 500g $360 2021-12-16 Buy
Arctom CFN97568 3,4-Dihydroxybenzoic Acid 20mg $30 2021-12-16 Buy
AvaChem 3289 Protocatechuic Acid 5mg $59 2021-12-16 Buy
AvaChem 3289 Protocatechuic Acid 20mg $119 2021-12-16 Buy
Biorbyt Ltd orb594219 Protocatechuic Acid 20mg $153 2021-12-16 Buy
Biorbyt Ltd orb594219 Protocatechuic Acid 1000mg $221 2021-12-16 Buy
Biorbyt Ltd orb105706 3,4-Dihydroxybenzoic acid >98%,Standard References Grade 20mg $569.5 2021-12-16 Buy

Properties

Melting point :197-200 °C (dec.) (lit.)
Boiling point :237.46°C (rough estimate)
Density :1.54
refractive index :1.6400 (estimate)
FEMA :4430 | 3,4-DIHYDROXYBENZOIC ACID
storage temp. :Store below +30°C.
solubility :20g/l
pka :4.48(at 25℃)
form :Fine Crystalline Powder
color :Beige to brown
PH :3.78(1 mM solution);3.25(10 mM solution);2.74(100 mM solution)
Odor :at 100.00 %. mild phenolic balsamic
Odor Type :phenolic
Water Solubility :Soluble in hot alcohol and ether. Slightly soluble in water.
Sensitive :Air Sensitive
Merck :14,7894
BRN :1448841
Stability :Stable. Incompatible with strong oxidizing agents, strong bases.
InChIKey :YQUVCSBJEUQKSH-UHFFFAOYSA-N
LogP :1.16
CAS DataBase Reference :99-50-3(CAS DataBase Reference)
EPA Substance Registry System :Protocatechuic acid (99-50-3)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Protocatechuic acid (PCA) is a dihydroxybenzoic acid phenolic compound found in many edible and medicinal plants. It is a major metabolite of antioxidant polyphenols found in green tea and demonstrates free radical scavenging capability in a 1,1-diphenyl-2-picrylhydrazyl radical scavenging activity assay (IC50 = 16.3 μM). It is thought to possess anti-inflammatory, antihyperglycemic, neuroprotective, and anticancer activities. Dietary administration of PCA dose dependently inhibits in vitro chemical carcinogenesis and exerts pro-apoptotic and anti-proliferative effects in different tissues. In studies of tumor cell migration and invasion using mouse melanoma B16/F10 cells, PCA at 0.1-2 mM down-regulated the Ras/Akt/NF-κB pathway by targeting RhoB activation, leading to a reduction of MMP-mediated activity.

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