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ChemicalBook >> CAS DataBase List >> Piperine

Piperine

Piperine price.
  • $14 - $1500
  • Product name: Piperine
  • CAS: 94-62-2
  • MF: C17H19NO3
  • MW: 285.34
  • EINECS:202-348-0
  • MDL Number:MFCD00005839
  • Synonyms:Piperine,98%;Piperidine, 1-(2E,4E)-5-(1,3-benzodioxol-5-yl)-1-oxo-2,4-pentadienyl-;1-piperinoylpiperidine;PIPERINE(P);PIPERINE(RG);PIPERLINE;Piperine SynonyMs (E,E)-1-[5-(1,3-Benzodioxol-5-yl)-1-oxo-2,4-pentadienyl]-piperidine;Piperine (E,E)-1-[5-(1,3-Benzodioxol-5-yl)-1-oxo-2,4-pentadienyl]-piperidine
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  • ManufacturerAK Scientific
  • Product numberJ10833
  • Product descriptionPiperine
  • Packaging100mg
  • Price$49.5
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ10833
  • Product descriptionPiperine
  • Packaging25mg
  • Price$28.6
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberV0140
  • Product descriptionPiperine
  • Packaging5g
  • Price$25
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberA13510
  • Product descriptionPiperine, 98%
  • Packaging5g
  • Price$29.6
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberA13510
  • Product descriptionPiperine, 98%
  • Packaging25g
  • Price$138
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberA13510
  • Product descriptionPiperine, 98%
  • Packaging100g
  • Price$399.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAmbeed
  • Product numberA126615
  • Product description(2E,4E)-5-(Benzo[d][1,3]dioxol-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one 97%
  • Packaging250mg
  • Price$14
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA126615
  • Product description(2E,4E)-5-(Benzo[d][1,3]dioxol-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one 97%
  • Packaging1g
  • Price$26
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA126615
  • Product description(2E,4E)-5-(Benzo[d][1,3]dioxol-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one 97%
  • Packaging5g
  • Price$49
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA126615
  • Product description(2E,4E)-5-(Benzo[d][1,3]dioxol-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one 97%
  • Packaging10g
  • Price$107
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA126615
  • Product description(2E,4E)-5-(Benzo[d][1,3]dioxol-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one 97%
  • Packaging25g
  • Price$313
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA126615
  • Product description(2E,4E)-5-(Benzo[d][1,3]dioxol-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one 97%
  • Packaging100g
  • Price$313
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBIDF1038
  • Product descriptionPiperine 96%
  • Packaging5g
  • Price$90
  • Updated2021-12-16
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  • ManufacturerApolloscientific
  • Product numberBIDF1038
  • Product descriptionPiperine 96%
  • Packaging25g
  • Price$141
  • Updated2021-12-16
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  • ManufacturerApolloscientific
  • Product numberBIDF1038
  • Product descriptionPiperine 96%
  • Packaging100g
  • Price$343
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN99919
  • Product descriptionPiperine ≥98%
  • Packaging20mg
  • Price$30
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific J10833 Piperine 100mg $49.5 2021-12-16 Buy
AK Scientific J10833 Piperine 25mg $28.6 2021-12-16 Buy
AK Scientific V0140 Piperine 5g $25 2021-12-16 Buy
Alfa Aesar A13510 Piperine, 98% 5g $29.6 2024-03-01 Buy
Alfa Aesar A13510 Piperine, 98% 25g $138 2024-03-01 Buy
Alfa Aesar A13510 Piperine, 98% 100g $399.65 2024-03-01 Buy
Ambeed A126615 (2E,4E)-5-(Benzo[d][1,3]dioxol-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one 97% 250mg $14 2021-12-16 Buy
Ambeed A126615 (2E,4E)-5-(Benzo[d][1,3]dioxol-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one 97% 1g $26 2021-12-16 Buy
Ambeed A126615 (2E,4E)-5-(Benzo[d][1,3]dioxol-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one 97% 5g $49 2021-12-16 Buy
Ambeed A126615 (2E,4E)-5-(Benzo[d][1,3]dioxol-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one 97% 10g $107 2021-12-16 Buy
Ambeed A126615 (2E,4E)-5-(Benzo[d][1,3]dioxol-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one 97% 25g $313 2021-12-16 Buy
Ambeed A126615 (2E,4E)-5-(Benzo[d][1,3]dioxol-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-one 97% 100g $313 2021-12-16 Buy
Apolloscientific BIDF1038 Piperine 96% 5g $90 2021-12-16 Buy
Apolloscientific BIDF1038 Piperine 96% 25g $141 2021-12-16 Buy
Apolloscientific BIDF1038 Piperine 96% 100g $343 2021-12-16 Buy
Arctom CFN99919 Piperine ≥98% 20mg $30 2021-12-16 Buy

Properties

Melting point :131-135 °C(lit.)
Boiling point :427.77°C (rough estimate)
Density :1.0864 (rough estimate)
refractive index :1.5400 (estimate)
FEMA :2909 | PIPERINE
storage temp. :Sealed in dry,Room Temperature
solubility :Slightly soluble in water, 10% soluble in alcohol, soluble only in certain oils
form :Crystalline Powder
pka :12.22(at 18℃)
color :Off-white to tan or yellow-tan
Odor :at 1.00 % in propylene glycol. pepper animal
Odor Type :spicy
Water Solubility :40 mg/L (18 ºC)
Merck :14,7472
JECFA Number :1600
BRN :90741
Stability :Stable. Incompatible with strong oxidizing agents.
InChIKey :MXXWOMGUGJBKIW-YPCIICBESA-N
LogP :2.66
CAS DataBase Reference :94-62-2(CAS DataBase Reference)
NIST Chemistry Reference :Piperine(94-62-2)
EPA Substance Registry System :2,4-Pentadien-1-one, 5-(1,3-benzodioxol-5-yl)-1-(1-piperidinyl)-, (2E,4E)- (94-62-2)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H411 Toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 2
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P273 Avoid release to the environment.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P391 Collect spillage. Hazardous to the aquatic environment
P501 Dispose of contents/container to..…

Description

Piperine is a natural alkaloid that can be isolated from black pepper. It activates transient receptor potential vanilloid type 1 receptor (TRPV1; EC50 = 38 μM) and modulates GABAA receptors (EC50s = 43-60 μM). At similar levels, piperine inhibits both monoamine oxidases (MAOs), with IC50 values of 21 and 7 μM for MAO-A and MAO-B, respectively. Like other natural compounds containing methylenedioxyphenyl substituents, piperine affects cytochrome P450 (CYP) isoforms, inhibiting CYP3A species (Ki ~ 5 μM) and increasing expression of CYP1A and CYP2B in liver. It also has a biphasic effect on P-glycoprotein activity.

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