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ChemicalBook >> CAS DataBase List >> PD153035 HCl

PD153035 HCl

PD153035 HCl price.
  • $60 - $1949.9
  • Product name: PD153035 HCl
  • CAS: 183322-45-4
  • MF: C16H14BrN3O2.HCl
  • MW: 0
  • EINECS:
  • MDL Number:MFCD01074805
  • Synonyms:PD 153035 hydrochloride, >=98%;SU-5271 (AG1517) HCl ,ZM 252868 HCl;6,7-Dimethoxy-4-[N-(3-bromophenyl)amino]quinazoline hydrochloride PD153035;4-Quinazolinamine, N-(3-bromophenyl)-6,7-dimethoxy-, monohydrochloride;6,7-Dimethoxy-4-[N-(3-bromophenyl)amino]quinazoline hydrochloride;N-(3-BroMophenyl)-6,7-diMethoxyquinazolin-4-aMine hydrochloride;ZM 252868;PD153035 (HCl salt)
37 prices
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Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • Chem-Impex
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Sigma-Aldrich
  • TCI Chemical
Package
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product numberX7470
  • Product descriptionPD153035HCl
  • Packaging5mg
  • Price$108
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA187704
  • Product descriptionN-(3-Bromophenyl)-6,7-dimethoxyquinazolin-4-aminehydrochloride 98+%
  • Packaging5mg
  • Price$92
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA187704
  • Product descriptionN-(3-Bromophenyl)-6,7-dimethoxyquinazolin-4-aminehydrochloride 98+%
  • Packaging10mg
  • Price$119
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA187704
  • Product descriptionN-(3-Bromophenyl)-6,7-dimethoxyquinazolin-4-aminehydrochloride 98+%
  • Packaging50mg
  • Price$200
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA187704
  • Product descriptionN-(3-Bromophenyl)-6,7-dimethoxyquinazolin-4-aminehydrochloride 98+%
  • Packaging100mg
  • Price$259
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA187704
  • Product descriptionN-(3-Bromophenyl)-6,7-dimethoxyquinazolin-4-aminehydrochloride 98+%
  • Packaging250mg
  • Price$388
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA187704
  • Product descriptionN-(3-Bromophenyl)-6,7-dimethoxyquinazolin-4-aminehydrochloride 98+%
  • Packaging1g
  • Price$1319
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0012841
  • Product descriptionPD-153035 HYDROCHLORIDE 95.00%
  • Packaging5MG
  • Price$168.3
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0012841
  • Product descriptionPD-153035 HYDROCHLORIDE 95.00%
  • Packaging10MG
  • Price$673.08
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb154722
  • Product descriptionPD153035 HCl (SU-5271, AG1517) >98%
  • Packaging100mg
  • Price$542.3
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb154722
  • Product descriptionPD153035 HCl (SU-5271, AG1517) >98%
  • Packaging250mg
  • Price$986
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb154722
  • Product descriptionPD153035 HCl (SU-5271, AG1517) >98%
  • Packaging1g
  • Price$1949.9
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB43340
  • Product description4-[(3-Bromophenyl)amino]-6,7-dimethoxyquinazoline hydrochloride
  • Packaging10mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB43340
  • Product description4-[(3-Bromophenyl)amino]-6,7-dimethoxyquinazoline hydrochloride
  • Packaging25mg
  • Price$170
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB43340
  • Product description4-[(3-Bromophenyl)amino]-6,7-dimethoxyquinazoline hydrochloride
  • Packaging50mg
  • Price$287.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB43340
  • Product description4-[(3-Bromophenyl)amino]-6,7-dimethoxyquinazoline hydrochloride
  • Packaging100mg
  • Price$460
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific X7470 PD153035HCl 5mg $108 2021-12-16 Buy
Ambeed A187704 N-(3-Bromophenyl)-6,7-dimethoxyquinazolin-4-aminehydrochloride 98+% 5mg $92 2021-12-16 Buy
Ambeed A187704 N-(3-Bromophenyl)-6,7-dimethoxyquinazolin-4-aminehydrochloride 98+% 10mg $119 2021-12-16 Buy
Ambeed A187704 N-(3-Bromophenyl)-6,7-dimethoxyquinazolin-4-aminehydrochloride 98+% 50mg $200 2021-12-16 Buy
Ambeed A187704 N-(3-Bromophenyl)-6,7-dimethoxyquinazolin-4-aminehydrochloride 98+% 100mg $259 2021-12-16 Buy
Ambeed A187704 N-(3-Bromophenyl)-6,7-dimethoxyquinazolin-4-aminehydrochloride 98+% 250mg $388 2021-12-16 Buy
Ambeed A187704 N-(3-Bromophenyl)-6,7-dimethoxyquinazolin-4-aminehydrochloride 98+% 1g $1319 2021-12-16 Buy
American Custom Chemicals Corporation API0012841 PD-153035 HYDROCHLORIDE 95.00% 5MG $168.3 2021-12-16 Buy
American Custom Chemicals Corporation API0012841 PD-153035 HYDROCHLORIDE 95.00% 10MG $673.08 2021-12-16 Buy
Biorbyt Ltd orb154722 PD153035 HCl (SU-5271, AG1517) >98% 100mg $542.3 2021-12-16 Buy
Biorbyt Ltd orb154722 PD153035 HCl (SU-5271, AG1517) >98% 250mg $986 2021-12-16 Buy
Biorbyt Ltd orb154722 PD153035 HCl (SU-5271, AG1517) >98% 1g $1949.9 2021-12-16 Buy
Biosynth Carbosynth FB43340 4-[(3-Bromophenyl)amino]-6,7-dimethoxyquinazoline hydrochloride 10mg $100 2021-12-16 Buy
Biosynth Carbosynth FB43340 4-[(3-Bromophenyl)amino]-6,7-dimethoxyquinazoline hydrochloride 25mg $170 2021-12-16 Buy
Biosynth Carbosynth FB43340 4-[(3-Bromophenyl)amino]-6,7-dimethoxyquinazoline hydrochloride 50mg $287.5 2021-12-16 Buy
Biosynth Carbosynth FB43340 4-[(3-Bromophenyl)amino]-6,7-dimethoxyquinazoline hydrochloride 100mg $460 2021-12-16 Buy

Properties

Melting point :265°C(lit.)
storage temp. :Sealed in dry,Room Temperature
solubility :DMSO: soluble2mg/mL, clear (warmed)
form :powder
color :white to beige

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger GHS hazard pictograms P280, P305+P351+P338, P310
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.

Description

Overactivity of the epidermal growth factor receptor-associated tyrosine kinase (EGFR) has been associated with cancer development and progression, including cell proliferation, apoptosis, angiogenesis, and metastatic spread. PD 153035 is a highly potent, reversible inhibitor of the EGFR (Ki = 5.2 pM; IC50 = 29 pM). It has been shown to rapidly suppress autophosphorylation of EGFR in ?broblasts and human epidermoid carcinoma cells, as well as to selectively block EGF-mediated cellular processes, including mitogenesis and early gene expression.

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