Nintedanib esylate
|
- $7 - $2233.8
- Product name: Nintedanib esylate
- CAS: 656247-18-6
- MF: C33H39N5O7S
- MW: 649.76
- EINECS:
- MDL Number:MFCD26142360
- Synonyms:(3Z)-2,3-Dihydro-3-[[[4-[methyl[2-(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-1H-indole-6-carboxylic acid methyl ester ethanesulfonate ;BIBF 1120 esylate;BIBF-1120 esylate;BIBF1120/nintedanib ethanesulfonate salt;Trinidad Neeb esylate;Intedanib ethanesulfonate;Nintedanib ethanesulfonate salt;Trinidad Neeb ethanesulfonate
35 prices
Selected condition：
Brand
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- Biorbyt Ltd
- Biosynth Carbosynth
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Labseeker
- Matrix Scientific
- TRC
Package
- 5MG
- 10mg
- 25mg
- 50mg
- 100mg
- 200mg
- 250mg
- 500mg
- 1g
- 2g
- 5g
- 10g
- ManufacturerAK Scientific
- Product number9942AL
- Product descriptionNintedanibesylate
- Packaging25mg
- Price$67.2
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ51091
- Product descriptionNintedanibesylate
- Packaging1g
- Price$178
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA160216
- Product description(Z)-Methyl3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylateethanesulfonate 98+%
- Packaging100mg
- Price$7
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA160216
- Product description(Z)-Methyl3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylateethanesulfonate 98+%
- Packaging250mg
- Price$14
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA160216
- Product description(Z)-Methyl3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylateethanesulfonate 98+%
- Packaging5g
- Price$136
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberCHM0292797
- Product description(3Z)-2,3-DIHYDRO-3-[[[4-[METHYL[2-(4-METHYL-1-PIPERAZINYL)ACETYL]AMINO]PHENYL]AMINO]PHENYLMETHYLENE]-2-OXO-1H-INDOLE-6-CARBOXYLIC ACID METHYL ESTER ETHANESULFONATE 95.00%
- Packaging5MG
- Price$497.93
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb180030
- Product descriptionNintedanib, Ethanesulfonate Salt >99%
- Packaging25mg
- Price$304.3
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb180030
- Product descriptionNintedanib, Ethanesulfonate Salt >99%
- Packaging50mg
- Price$357
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb180030
- Product descriptionNintedanib, Ethanesulfonate Salt >99%
- Packaging100mg
- Price$414.8
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb180030
- Product descriptionNintedanib, Ethanesulfonate Salt >99%
- Packaging200mg
- Price$433.5
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb180030
- Product descriptionNintedanib, Ethanesulfonate Salt >99%
- Packaging500mg
- Price$671.5
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb180030
- Product descriptionNintedanib, Ethanesulfonate Salt >99%
- Packaging1g
- Price$705.5
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb180030
- Product descriptionNintedanib, Ethanesulfonate Salt >99%
- Packaging2g
- Price$1174.7
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb180030
- Product descriptionNintedanib, Ethanesulfonate Salt >99%
- Packaging5G
- Price$2233.8
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFD71497
- Product descriptionNintedanib ethanesulfonate
- Packaging25mg
- Price$60
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFD71497
- Product descriptionNintedanib ethanesulfonate
- Packaging50mg
- Price$100
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 9942AL | Nintedanibesylate | 25mg | $67.2 | 2021-12-16 | Buy |
| AK Scientific | J51091 | Nintedanibesylate | 1g | $178 | 2021-12-16 | Buy |
| Ambeed | A160216 | (Z)-Methyl3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylateethanesulfonate 98+% | 100mg | $7 | 2021-12-16 | Buy |
| Ambeed | A160216 | (Z)-Methyl3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylateethanesulfonate 98+% | 250mg | $14 | 2021-12-16 | Buy |
| Ambeed | A160216 | (Z)-Methyl3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylateethanesulfonate 98+% | 5g | $136 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0292797 | (3Z)-2,3-DIHYDRO-3-[[[4-[METHYL[2-(4-METHYL-1-PIPERAZINYL)ACETYL]AMINO]PHENYL]AMINO]PHENYLMETHYLENE]-2-OXO-1H-INDOLE-6-CARBOXYLIC ACID METHYL ESTER ETHANESULFONATE 95.00% | 5MG | $497.93 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb180030 | Nintedanib, Ethanesulfonate Salt >99% | 25mg | $304.3 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb180030 | Nintedanib, Ethanesulfonate Salt >99% | 50mg | $357 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb180030 | Nintedanib, Ethanesulfonate Salt >99% | 100mg | $414.8 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb180030 | Nintedanib, Ethanesulfonate Salt >99% | 200mg | $433.5 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb180030 | Nintedanib, Ethanesulfonate Salt >99% | 500mg | $671.5 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb180030 | Nintedanib, Ethanesulfonate Salt >99% | 1g | $705.5 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb180030 | Nintedanib, Ethanesulfonate Salt >99% | 2g | $1174.7 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb180030 | Nintedanib, Ethanesulfonate Salt >99% | 5G | $2233.8 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD71497 | Nintedanib ethanesulfonate | 25mg | $60 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD71497 | Nintedanib ethanesulfonate | 50mg | $100 | 2021-12-16 | Buy |
Properties
Melting point :>233°C (dec.)
storage temp. :-20°C Freezer
solubility :DMSO (Slightly), Methanol (Slightly)
form :Yellow solid.
color :Light Yellow to Yellow
InChIKey :MMMVNAGRWOJNMW-FJBFXRHMSA-N
SMILES :S(O)(=O)(=O)CC.C(/C1C=CC=CC=1)(=C1\C(NC2=CC(C(=O)OC)=CC=C\12)=O)\NC1C=CC(N(C)C(=O)CN2CCN(C)CC2)=CC=1
storage temp. :-20°C Freezer
solubility :DMSO (Slightly), Methanol (Slightly)
form :Yellow solid.
color :Light Yellow to Yellow
InChIKey :MMMVNAGRWOJNMW-FJBFXRHMSA-N
SMILES :S(O)(=O)(=O)CC.C(/C1C=CC=CC=1)(=C1\C(NC2=CC(C(=O)OC)=CC=C\12)=O)\NC1C=CC(N(C)C(=O)CN2CCN(C)CC2)=CC=1
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||||||||||||||||
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Description
Nintedanib esylate is a potent, oral triple angiokinase inhibitor developed by Boehringer Ingelheim that targets proangiogenic and pro-fibrotic pathways mediated by the vascular endothelial growth factor receptor, fibroblast growth factor receptor and plateletderived growth factor receptor families, as well as Src and Flt-3 kinases. It was approved for the treatment of idiopathic pulmonary fibrosis (IPF), a condition in which the lungs become progressively scarred over time, by the US FDA in October 2014 and by the EMA in January 2015. The FDA granted nintedanib esylate fast-track, priority review, orphan product, and breakthrough designations. The drug was also approved by the EMA in November 2014 for treatment of non-small cell lung cancer in combination with docetaxel after first-line chemotherapy.More related product prices
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- 14192-26-8
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$50-641
Suppliers and manufacturers
Cangzhou Kangrui Pharma Tech Co. Ltd.,
Shanghai Daken Advanced Materials Co.,Ltd
Beijing Cooperate Pharmaceutical Co.,Ltd
Shanghai Bojing Chemical Co.,Ltd.
Henan Tianfu Chemical Co.,Ltd.
Hangzhou FandaChem Co.,Ltd.
Nanjing ChemLin Chemical Industry Co., Ltd.
