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ChemicalBook >> CAS DataBase List >> Lonidamine

Lonidamine

Lonidamine price.
  • $10 - $1504.5
  • Product name: Lonidamine
  • CAS: 50264-69-2
  • MF: C15H10Cl2N2O2
  • MW: 321.16
  • EINECS:256-510-0
  • MDL Number:MFCD00866285
  • Synonyms:af1890 ;1-[(2,4-dichlorophenyl)methyl]indazole-3-carboxylic acid;1H-Indazole-3-carboxylicacid, 1-[(2,4-dichlorophenyl)Methyl]-;1-(2,4-dichlorbenzyl)-indazole-3-carboxylicacid ;1-(2,4-dichlorobenzyl)-1h-indazole-3-carboxylicaci ;Lonidamine, >=99%;1-(3,4-dichlorobenzyl)-1H-indazole-3-carboxylic acid;DICLONDAZOLIC ACID
33 prices
Selected condition:
Brand
  • AK Scientific
  • Arctom
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • Sigma-Aldrich
  • Tocris
  • Usbiological
Package
  • 50
  • 5mg
  • 10mg
  • 10
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 500mg
  • 1g
  • 5g
  • ManufacturerAK Scientific
  • Product numberC483
  • Product descriptionLonidamine
  • Packaging25mg
  • Price$94
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS526212
  • Product description1-(2,4-Dichlorobenzyl)-1H-indazole-3-carboxylicacid ≥99%
  • Packaging5mg
  • Price$10
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS526212
  • Product description1-(2,4-Dichlorobenzyl)-1H-indazole-3-carboxylicacid ≥99%
  • Packaging10mg
  • Price$13
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS526212
  • Product description1-(2,4-Dichlorobenzyl)-1H-indazole-3-carboxylicacid ≥99%
  • Packaging50mg
  • Price$26
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS526212
  • Product description1-(2,4-Dichlorobenzyl)-1H-indazole-3-carboxylicacid ≥99%
  • Packaging100mg
  • Price$48
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS526212
  • Product description1-(2,4-Dichlorobenzyl)-1H-indazole-3-carboxylicacid ≥99%
  • Packaging250mg
  • Price$72
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS526212
  • Product description1-(2,4-Dichlorobenzyl)-1H-indazole-3-carboxylicacid ≥99%
  • Packaging1g
  • Price$175
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS526212
  • Product description1-(2,4-Dichlorobenzyl)-1H-indazole-3-carboxylicacid ≥99%
  • Packaging5g
  • Price$631
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb134504
  • Product descriptionLonidamine >99%
  • Packaging100mg
  • Price$510
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb134504
  • Product descriptionLonidamine >99%
  • Packaging250mg
  • Price$765
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb134504
  • Product descriptionLonidamine >99%
  • Packaging1g
  • Price$1504.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFL32739
  • Product descriptionLonidamine
  • Packaging10mg
  • Price$40
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFL32739
  • Product descriptionLonidamine
  • Packaging50mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number14640
  • Product descriptionLonidamine ≥98%
  • Packaging5mg
  • Price$49
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14640
  • Product descriptionLonidamine ≥98%
  • Packaging10mg
  • Price$77
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14640
  • Product descriptionLonidamine ≥98%
  • Packaging50mg
  • Price$168
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific C483 Lonidamine 25mg $94 2021-12-16 Buy
Arctom AS526212 1-(2,4-Dichlorobenzyl)-1H-indazole-3-carboxylicacid ≥99% 5mg $10 2021-12-16 Buy
Arctom AS526212 1-(2,4-Dichlorobenzyl)-1H-indazole-3-carboxylicacid ≥99% 10mg $13 2021-12-16 Buy
Arctom AS526212 1-(2,4-Dichlorobenzyl)-1H-indazole-3-carboxylicacid ≥99% 50mg $26 2021-12-16 Buy
Arctom AS526212 1-(2,4-Dichlorobenzyl)-1H-indazole-3-carboxylicacid ≥99% 100mg $48 2021-12-16 Buy
Arctom AS526212 1-(2,4-Dichlorobenzyl)-1H-indazole-3-carboxylicacid ≥99% 250mg $72 2021-12-16 Buy
Arctom AS526212 1-(2,4-Dichlorobenzyl)-1H-indazole-3-carboxylicacid ≥99% 1g $175 2021-12-16 Buy
Arctom AS526212 1-(2,4-Dichlorobenzyl)-1H-indazole-3-carboxylicacid ≥99% 5g $631 2021-12-16 Buy
Biorbyt Ltd orb134504 Lonidamine >99% 100mg $510 2021-12-16 Buy
Biorbyt Ltd orb134504 Lonidamine >99% 250mg $765 2021-12-16 Buy
Biorbyt Ltd orb134504 Lonidamine >99% 1g $1504.5 2021-12-16 Buy
Biosynth Carbosynth FL32739 Lonidamine 10mg $40 2021-12-16 Buy
Biosynth Carbosynth FL32739 Lonidamine 50mg $100 2021-12-16 Buy
Cayman Chemical 14640 Lonidamine ≥98% 5mg $49 2024-03-01 Buy
Cayman Chemical 14640 Lonidamine ≥98% 10mg $77 2024-03-01 Buy
Cayman Chemical 14640 Lonidamine ≥98% 50mg $168 2024-03-01 Buy

Properties

Melting point :207-209°C
Boiling point :537.9±45.0 °C(Predicted)
Density :1.4835 (rough estimate)
refractive index :1.6070 (estimate)
storage temp. :Sealed in dry,2-8°C
solubility :Soluble in DMSO (up to 25 mg/ml).
form :solid
pka :3.00±0.10(Predicted)
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
InChIKey :WDRYRZXSPDWGEB-UHFFFAOYSA-N
CAS DataBase Reference :50264-69-2(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H360 May damage fertility or the unborn child Reproductive toxicity Category 1A, 1B Danger GHS hazard pictograms
Precautionary statements:
P201 Obtain special instructions before use.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

Lonidamine is a derivative of indazole-3-carboxylic acid. It is a kind of orally administrated small molecule, which can inhibit the glycolysis process through inactivating the hexokinase (the first step in glycolysis). It has been shown that cancer cell primarily generates energy through glycolysis process. Therefore, Lonidamine has been used for the treatment of several kinds of cancers. One special property of Lonidamine is that it seems to enhance aerobic glycolysis in normal cells, but inhibit glycolysis only in cancer cells. In addition, there are also evidences that Lonidamine may increase the occurrence of apoptosis. It has also been shown that Lonidamine is effective in the treatment of benigh prostatic hyperplasia (BPH).

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