REVIEW Lonidamine is an orally administered small molecule that inhibits glycolysis by the inactivation of hexokinase. This compound has anticancer and antispermatogenic agent in vitro and in vivo. It may increase programmed cell death and trigger apoptosis.
REFERENCES
[1]
Floridi A; Paggi M G; Marcante M L; Silvestrini B; Caputo A; De Martino C. Lonidamine, a selective inhibitor of aerobic glycolysis of murine tumor cells. Journal of the National Cancer Institute. (1981) 66(3): 497-9.
[2]
Silvestrini B; Palazzo G; De Gregorio M. Lonidamine and related compounds. Progress in Medicinal Chemistry. (1984) 21: 110-35.
[3]
Di Cosimo, Serena; Ferretti, Gianluigi; Papaldo, Paola; Carlini, Paolo; Fabi, Alessandra; Cognetti, Francesco. Lonidamine: efficacy and safety in clinical trials for the treatment of solid tumors. Drugs of Today. (2003) 39(3): 157-173.
[4]
Palazzo, Giuseppe; Silvestrini, Bruno 1-Benzylindazole-3-carboxylic acid derivatives Ger. Offen. (1973), DE 2310031 A1 19730920.
All products are stocked and shipped from the SF Bay, California, USA via FedEx, UPS or DHL.
All batches backed with full quality assurance.
??
All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.
These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.
Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.
New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.
Add to Favorites 
Delete from Favorites 
