Guanidine hydrochloride
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- $5 - $13385
- Product name: Guanidine hydrochloride
- CAS: 50-01-1
- MF: CH5N3.ClH
- MW: 95.53
- EINECS:200-002-3
- MDL Number:MFCD00013026
- Synonyms:guanidine,monohydrochloride ;guanidinechloride ;Guanidinemonohydrochloride ;AMINOFORMAMIDINE HCL;AMINOFORMAMIDINE HYDROCHLORIDE;AMINOMETHANAMIDINE HCL;AMINOMETHANAMIDINE HYDROCHLORIDE;Guanidine HCL（Low Ash)
100 prices
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Brand
- Adipogen Life Sciences
- AK Scientific
- Alfa Aesar
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Apolloscientific
- Aronis compounds
- ChemScene
- Matrix Scientific
- Medical Isotopes, Inc.
- Oakwood
- Sigma-Aldrich
- SynQuest Laboratories
- TCI Chemical
- Tocris
- TRC
- Usbiological
Package
- 20mg
- 100mg
- 500mg
- 2.500g
- 5g
- 10g
- 25g
- 50g
- 100ml
- 100g
- 10mM(in 1mL H2O)
- 250g
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- 1kg
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- 3KG
- 5000g
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- 50kg
- 1KT
- 1KIT
- ManufacturerAdipogen Life Sciences
- Product numberCDX-G0040-G100
- Product descriptionGuanidine hydrochloride ≥99%(Titration)
- Packaging100g
- Price$47
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberD014
- Product descriptionGuanidine hydrochloride
- Packaging500g
- Price$57
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberA13543
- Product descriptionGuanidine hydrochloride, 98%
- Packaging250g
- Price$29.2
- Updated2024-03-01
- Buy
- ManufacturerAlfa Aesar
- Product numberJ60786
- Product descriptionGuanidine hydrochloride, 99+%
- Packaging100g
- Price$59.5
- Updated2024-03-01
- Buy
- ManufacturerAlfa Aesar
- Product numberJ65485
- Product descriptionGuanidine hydrochloride, ultrapure, 99%
- Packaging100g
- Price$67.6
- Updated2024-03-01
- Buy
- ManufacturerAlfa Aesar
- Product numberJ75823
- Product descriptionGuanidine hydrochloride, 99.5+%, Molecular Biology Grade, Affymetrix/USB
- Packaging100g
- Price$68.4
- Updated2024-03-01
- Buy
- ManufacturerAlfa Aesar
- Product numberA13543
- Product descriptionGuanidine hydrochloride, 98%
- Packaging1000g
- Price$81.6
- Updated2024-03-01
- Buy
- ManufacturerAlfa Aesar
- Product numberJ65661
- Product descriptionGuanidine hydrochloride, Molecular Biology Grade
- Packaging100g
- Price$89.3
- Updated2024-03-01
- Buy
- ManufacturerAlfa Aesar
- Product numberJ60786
- Product descriptionGuanidine hydrochloride, 99+%
- Packaging1kg
- Price$346
- Updated2024-03-01
- Buy
- ManufacturerAlfa Aesar
- Product numberJ65485
- Product descriptionGuanidine hydrochloride, ultrapure, 99%
- Packaging1kg
- Price$389
- Updated2024-03-01
- Buy
- ManufacturerAlfa Aesar
- Product numberJ75823
- Product descriptionGuanidine hydrochloride, 99.5+%, Molecular Biology Grade, Affymetrix/USB
- Packaging5kg
- Price$993
- Updated2024-03-01
- Buy
- ManufacturerAlfa Aesar
- Product numberJ60786
- Product descriptionGuanidine hydrochloride, 99+%
- Packaging500g
- Price$200
- Updated2024-03-01
- Buy
- ManufacturerAlfa Aesar
- Product numberJ75823
- Product descriptionGuanidine hydrochloride, 99.5+%, Molecular Biology Grade, Affymetrix/USB
- Packaging500g
- Price$223
- Updated2024-03-01
- Buy
- ManufacturerAlfa Aesar
- Product numberJ65485
- Product descriptionGuanidine hydrochloride, ultrapure, 99%
- Packaging500g
- Price$227
- Updated2024-03-01
- Buy
- ManufacturerAlfa Aesar
- Product numberA13543
- Product descriptionGuanidine hydrochloride, 98%
- Packaging5000g
- Price$292
- Updated2024-03-01
- Buy
- ManufacturerAlfa Aesar
- Product numberJ65661
- Product descriptionGuanidine hydrochloride, Molecular Biology Grade
- Packaging500g
- Price$304
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | CDX-G0040-G100 | Guanidine hydrochloride ≥99%(Titration) | 100g | $47 | 2021-12-16 | Buy |
| AK Scientific | D014 | Guanidine hydrochloride | 500g | $57 | 2021-12-16 | Buy |
| Alfa Aesar | A13543 | Guanidine hydrochloride, 98% | 250g | $29.2 | 2024-03-01 | Buy |
| Alfa Aesar | J60786 | Guanidine hydrochloride, 99+% | 100g | $59.5 | 2024-03-01 | Buy |
| Alfa Aesar | J65485 | Guanidine hydrochloride, ultrapure, 99% | 100g | $67.6 | 2024-03-01 | Buy |
| Alfa Aesar | J75823 | Guanidine hydrochloride, 99.5+%, Molecular Biology Grade, Affymetrix/USB | 100g | $68.4 | 2024-03-01 | Buy |
| Alfa Aesar | A13543 | Guanidine hydrochloride, 98% | 1000g | $81.6 | 2024-03-01 | Buy |
| Alfa Aesar | J65661 | Guanidine hydrochloride, Molecular Biology Grade | 100g | $89.3 | 2024-03-01 | Buy |
| Alfa Aesar | J60786 | Guanidine hydrochloride, 99+% | 1kg | $346 | 2024-03-01 | Buy |
| Alfa Aesar | J65485 | Guanidine hydrochloride, ultrapure, 99% | 1kg | $389 | 2024-03-01 | Buy |
| Alfa Aesar | J75823 | Guanidine hydrochloride, 99.5+%, Molecular Biology Grade, Affymetrix/USB | 5kg | $993 | 2024-03-01 | Buy |
| Alfa Aesar | J60786 | Guanidine hydrochloride, 99+% | 500g | $200 | 2024-03-01 | Buy |
| Alfa Aesar | J75823 | Guanidine hydrochloride, 99.5+%, Molecular Biology Grade, Affymetrix/USB | 500g | $223 | 2024-03-01 | Buy |
| Alfa Aesar | J65485 | Guanidine hydrochloride, ultrapure, 99% | 500g | $227 | 2024-03-01 | Buy |
| Alfa Aesar | A13543 | Guanidine hydrochloride, 98% | 5000g | $292 | 2024-03-01 | Buy |
| Alfa Aesar | J65661 | Guanidine hydrochloride, Molecular Biology Grade | 500g | $304 | 2024-03-01 | Buy |
Properties
Melting point :180-185 °C(lit.)
Density :1.18 g/mL at 25 °C(lit.)
refractive index :n20/D 1.465
storage temp. :room temp
solubility :H2O: 6 M, clear, colorless
form :Crystals
color :White to slightly yellow
PH :4.5-5.5 (100g/l, H2O, 20℃)
Odor :Odorless
PH Range :4.5 - 6.0 at 573 g/l at 25 °C
Water Solubility :2280 g/L (20 ºC)
Sensitive :Hygroscopic
λmax :λ: 260 nm Amax: 0.040
λ: 280 nm Amax: 0.025 Merck :14,4562
BRN :3591990
Stability :Stable. Hygroscopic. Incompatible with strong oxidizing agents.
InChIKey :PJJJBBJSCAKJQF-UHFFFAOYSA-N
CAS DataBase Reference :50-01-1(CAS DataBase Reference)
EPA Substance Registry System :Guanidine monohydrochloride (50-01-1)
Density :1.18 g/mL at 25 °C(lit.)
refractive index :n
storage temp. :room temp
solubility :H2O: 6 M, clear, colorless
form :Crystals
color :White to slightly yellow
PH :4.5-5.5 (100g/l, H2O, 20℃)
Odor :Odorless
PH Range :4.5 - 6.0 at 573 g/l at 25 °C
Water Solubility :2280 g/L (20 ºC)
Sensitive :Hygroscopic
λmax :λ: 260 nm Amax: 0.040
λ: 280 nm Amax: 0.025 Merck :14,4562
BRN :3591990
Stability :Stable. Hygroscopic. Incompatible with strong oxidizing agents.
InChIKey :PJJJBBJSCAKJQF-UHFFFAOYSA-N
CAS DataBase Reference :50-01-1(CAS DataBase Reference)
EPA Substance Registry System :Guanidine monohydrochloride (50-01-1)
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||
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Description
Guanidine hydrochloride is a strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant.It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC.Guanidine Hydrochloride is the hydrochloride salt form of guanidine, a strong basic compound with parasympathomimetic activity. Guanidine hydrochloride enhances the release of acetylcholine following a nerve impulse and potentiates acetylcholine actions on muscarinic and nicotinic receptors. It also appears to slow the rates of depolarization and repolarization of muscle cell membranes.
Guanidine Hydrochloride is a powerful, chaotropic agent which is widely used for purification of proteins and nucleic acids. Guanidine Hydrochloride is useful for denaturation and refolding of proteins as well as in the recovery of periplasmic proteins and isolation of RNA. At higher concentrations, this strong denaturant has been reported to solubilize denatured insoluble proteins such as inclusion bodies. When utilized at lower concentrations, Guanidine Hydrochloride is noted to be useful in prompting the refolding of denatured proteins. Guanidine Hydrochloride is also been reported to allow return of enzymatic activity in protocols using Guanidine Hydrochloride as a first step. Guanidine Hydrochloride is an inhibitor of RNase.
Guanidine hydrochloride is used for purification of proteins and nucleic acids. It can be used as a medicine, organic synthesis intermediate and is used in dyes. It acts as an intermediate in the preparation of sulfadiazine, which is an important raw material for sulfamethyldiazine, sulfamethazine and folic acid. It is utilized in the synthesis of 2-amino-pyrimidine, 2-amino-6-methyl-pyrimidine and 2-amino-4,6-dimethyl-pyrimidine. Also used in RNA isolation to dissociate nucleoproteins and inhibit RNase.
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Suppliers and manufacturers
Dayang Chem (Hangzhou) Co.,Ltd.
Hefei TNJ Chemical Industry Co.,Ltd.
