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ChemicalBook >> CAS DataBase List >> Duloxetine hydrochloride

Duloxetine hydrochloride

Duloxetine hydrochloride price.
  • $30 - $2709
  • Product name: Duloxetine hydrochloride
  • CAS: 136434-34-9
  • MF: C18H20ClNOS
  • MW: 333.88
  • EINECS:603-962-5
  • MDL Number:MFCD06407958
  • Synonyms:LY-248686 HCl;(γS)-N-methyl-γ-(1-naphthalenyloxy)-2-thiophenepropanamine, hydrochloride (1:1);(+)-N-Methyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propanamine hydrochloride;LY-248686 hydrochloride;Duloxetine for system suitability;Duloxetine hydrochloride solution;(S)-N-Methyl-3-(1-naphthalenyloxy)-3-(2-thienyl) propanamine hydrochloride;Methanol( Test Duloxetine HCl, 1.0 mg/mL as free base)
51 prices
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Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • AvaChem
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • Chem-Impex
  • ChemScene
  • Chemtos
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Oakwood
  • Sigma-Aldrich
  • TCI Chemical
  • Tocris
  • TRC
  • Usbiological
Package
  • 10MG
  • 25mg
  • 5MG
  • y0001454
  • 50mg
  • 100mg
  • 50
  • y0001453
  • 10
  • 250mg
  • 500mg
  • 1mL
  • 1g
  • 5g
  • 10g
  • 25g
  • 10mM(in 1mL DMSO)
  • ManufacturerAK Scientific
  • Product numberJ10476
  • Product description(S)-DuloxetineHCl
  • Packaging250mg
  • Price$46
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberA558
  • Product description(S)-DuloxetineHCl
  • Packaging1g
  • Price$67
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ98826
  • Product description(S)-DuloxetineHCl
  • Packaging10g
  • Price$250
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ10476
  • Product description(S)-DuloxetineHCl
  • Packaging5g
  • Price$301
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0002507
  • Product description(S)-DULOXETINE HYDROCHLORIDE 95.00%
  • Packaging5MG
  • Price$511
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0002507
  • Product description(S)-DULOXETINE HYDROCHLORIDE 95.00%
  • Packaging10MG
  • Price$658.55
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8421
  • Product descriptionDuloxetineHCl
  • Packaging10mM(in 1mL DMSO)
  • Price$55
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8421
  • Product descriptionDuloxetineHCl
  • Packaging10mg
  • Price$77
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8421
  • Product descriptionDuloxetineHCl
  • Packaging100mg
  • Price$130
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2477
  • Product descriptionDuloxetine Hydrochloride
  • Packaging250mg
  • Price$45
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2477
  • Product descriptionDuloxetine Hydrochloride
  • Packaging1g
  • Price$95
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2477
  • Product descriptionDuloxetine Hydrochloride
  • Packaging5g
  • Price$290
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberBD165546
  • Product descriptionDuloxetine hydrochloride
  • Packaging10mg
  • Price$55
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number14317
  • Product description(S)-Duloxetine (hydrochloride) ≥98%
  • Packaging10mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14317
  • Product description(S)-Duloxetine (hydrochloride) ≥98%
  • Packaging25mg
  • Price$60
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14317
  • Product description(S)-Duloxetine (hydrochloride) ≥98%
  • Packaging50mg
  • Price$100
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific J10476 (S)-DuloxetineHCl 250mg $46 2021-12-16 Buy
AK Scientific A558 (S)-DuloxetineHCl 1g $67 2021-12-16 Buy
AK Scientific J98826 (S)-DuloxetineHCl 10g $250 2021-12-16 Buy
AK Scientific J10476 (S)-DuloxetineHCl 5g $301 2021-12-16 Buy
American Custom Chemicals Corporation API0002507 (S)-DULOXETINE HYDROCHLORIDE 95.00% 5MG $511 2021-12-16 Buy
American Custom Chemicals Corporation API0002507 (S)-DULOXETINE HYDROCHLORIDE 95.00% 10MG $658.55 2021-12-16 Buy
ApexBio Technology A8421 DuloxetineHCl 10mM(in 1mL DMSO) $55 2021-12-16 Buy
ApexBio Technology A8421 DuloxetineHCl 10mg $77 2021-12-16 Buy
ApexBio Technology A8421 DuloxetineHCl 100mg $130 2021-12-16 Buy
AvaChem 2477 Duloxetine Hydrochloride 250mg $45 2021-12-16 Buy
AvaChem 2477 Duloxetine Hydrochloride 1g $95 2021-12-16 Buy
AvaChem 2477 Duloxetine Hydrochloride 5g $290 2021-12-16 Buy
Biosynth Carbosynth BD165546 Duloxetine hydrochloride 10mg $55 2021-12-16 Buy
Cayman Chemical 14317 (S)-Duloxetine (hydrochloride) ≥98% 10mg $32 2024-03-01 Buy
Cayman Chemical 14317 (S)-Duloxetine (hydrochloride) ≥98% 25mg $60 2024-03-01 Buy
Cayman Chemical 14317 (S)-Duloxetine (hydrochloride) ≥98% 50mg $100 2024-03-01 Buy

Properties

Melting point :118-122°C
Flash point :9℃
storage temp. :room temp
solubility :H2O: soluble5mg/mL (clear solution, warmed)
pka :pKa in DMF-water (66:34): 9.6(at 25℃)
form :powder
color :white to beige
optical activity :[α]/D +116 to +125°, c = 1 in methanol
Merck :14,3465
InChI :InChI=1/C18H19NOS.ClH/c1-19-12-11-17(18-10-5-13-21-18)20-16-9-4-7-14-6-2-3-8-15(14)16;/h2-10,13,17,19H,11-12H2,1H3;1H/t17-;/s3
InChIKey :BFFSMCNJSOPUAY-VOPAOICTNA-N
SMILES :C1(=CC=CS1)[C@H](CCNC)OC1=CC=CC2=CC=CC=C12.Cl |&1:5,r|

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:

Description

(S)-Duloxetine is a potent inhibitor of serotonin and norepinephrine reuptake (Kis = 4.6 and 15.6 nM, respectively, for rat synaptosomes). It less effectively inhibits dopamine reuptake (Ki = 369 nM). It is effective in cells, tissues, and in vivo. (S)-Duloxetine has applications in many chronic medical conditions, including major depressive disorder, generalized anxiety disorder, chronic neuropathic and musculoskeletal pain, and fibromyalgia.

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