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ChemicalBook >> CAS DataBase List >> Acyclovir

Acyclovir

Acyclovir price.
  • $5 - $765
  • Product name: Acyclovir
  • CAS: 59277-89-3
  • MF: C8H11N5O3
  • MW: 225.2
  • EINECS:261-685-1
  • MDL Number:MFCD00057880
  • Synonyms:1,9-dihydro-2-amino-9-((2-hydroxyethoxy)methyl)-6h-purin-6-on ;2-amino-1,9-dihydro-9-((2-hydroxyethoxy)-methyl)-6h-purin-6-on ;aciclovirum(latin) ;acielovir;cycloguanosine;Zoviax;2-amino-1,9-dihydro-9-((2-hydroxyethoxy)methyl)-6h-purin-6-one;2-AMINO-9-(2-HYDROXY-ETHOXYMETHYL)-1,9-DIHYDRO-PURIN-6-ONE
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  • AK Scientific
  • Alfa Aesar
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  • ApexBio Technology
  • Apolloscientific
  • Arctom
  • Aronis compounds
  • Axon Medchem
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  • Biosynth Carbosynth
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  • ChemScene
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  • a0220000
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  • 10mM(in 1mL DMSO)
  • 250g
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  • ManufacturerAK Scientific
  • Product numberF872
  • Product descriptionAcycloguanosine
  • Packaging25g
  • Price$37
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberF872
  • Product descriptionAcycloguanosine
  • Packaging500g
  • Price$319
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ64144
  • Product descriptionAcycloguanosine, 98%
  • Packaging1g
  • Price$72.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ64144
  • Product descriptionAcycloguanosine, 98%
  • Packaging5g
  • Price$215.65
  • Updated2024-03-01
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  • ManufacturerAlfa Aesar
  • Product numberJ64144
  • Product descriptionAcycloguanosine, 98%
  • Packaging25g
  • Price$654
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA118981
  • Product description2-Amino-9-((2-hydroxyethoxy)methyl)-1H-purin-6(9H)-one 98+%
  • Packaging5g
  • Price$8
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA118981
  • Product description2-Amino-9-((2-hydroxyethoxy)methyl)-1H-purin-6(9H)-one 98+%
  • Packaging25g
  • Price$21
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA118981
  • Product description2-Amino-9-((2-hydroxyethoxy)methyl)-1H-purin-6(9H)-one 98+%
  • Packaging100g
  • Price$57
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8644
  • Product descriptionAcyclovir
  • Packaging10mM(in 1mL DMSO)
  • Price$50
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberA8644
  • Product descriptionAcyclovir
  • Packaging50mg
  • Price$58
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberOR9240T
  • Product descriptionAcyclovir
  • Packaging100mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS013985
  • Product description2-Amino-9-((2-hydroxyethoxy)methyl)-1H-purin-6(9H)-one ≥98%
  • Packaging250mg
  • Price$5
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS013985
  • Product description2-Amino-9-((2-hydroxyethoxy)methyl)-1H-purin-6(9H)-one ≥98%
  • Packaging1g
  • Price$7
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS013985
  • Product description2-Amino-9-((2-hydroxyethoxy)methyl)-1H-purin-6(9H)-one ≥98%
  • Packaging5g
  • Price$9
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS013985
  • Product description2-Amino-9-((2-hydroxyethoxy)methyl)-1H-purin-6(9H)-one ≥98%
  • Packaging10g
  • Price$15
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS013985
  • Product description2-Amino-9-((2-hydroxyethoxy)methyl)-1H-purin-6(9H)-one ≥98%
  • Packaging25g
  • Price$21
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific F872 Acycloguanosine 25g $37 2021-12-16 Buy
AK Scientific F872 Acycloguanosine 500g $319 2021-12-16 Buy
Alfa Aesar J64144 Acycloguanosine, 98% 1g $72.65 2024-03-01 Buy
Alfa Aesar J64144 Acycloguanosine, 98% 5g $215.65 2024-03-01 Buy
Alfa Aesar J64144 Acycloguanosine, 98% 25g $654 2021-12-16 Buy
Ambeed A118981 2-Amino-9-((2-hydroxyethoxy)methyl)-1H-purin-6(9H)-one 98+% 5g $8 2021-12-16 Buy
Ambeed A118981 2-Amino-9-((2-hydroxyethoxy)methyl)-1H-purin-6(9H)-one 98+% 25g $21 2021-12-16 Buy
Ambeed A118981 2-Amino-9-((2-hydroxyethoxy)methyl)-1H-purin-6(9H)-one 98+% 100g $57 2021-12-16 Buy
ApexBio Technology A8644 Acyclovir 10mM(in 1mL DMSO) $50 2021-12-16 Buy
ApexBio Technology A8644 Acyclovir 50mg $58 2021-12-16 Buy
Apolloscientific OR9240T Acyclovir 100mg $60 2021-12-16 Buy
Arctom AS013985 2-Amino-9-((2-hydroxyethoxy)methyl)-1H-purin-6(9H)-one ≥98% 250mg $5 2021-12-16 Buy
Arctom AS013985 2-Amino-9-((2-hydroxyethoxy)methyl)-1H-purin-6(9H)-one ≥98% 1g $7 2021-12-16 Buy
Arctom AS013985 2-Amino-9-((2-hydroxyethoxy)methyl)-1H-purin-6(9H)-one ≥98% 5g $9 2021-12-16 Buy
Arctom AS013985 2-Amino-9-((2-hydroxyethoxy)methyl)-1H-purin-6(9H)-one ≥98% 10g $15 2021-12-16 Buy
Arctom AS013985 2-Amino-9-((2-hydroxyethoxy)methyl)-1H-purin-6(9H)-one ≥98% 25g $21 2021-12-16 Buy

Properties

Melting point :256-257°C
Boiling point :366.71°C (rough estimate)
Density :1.3654 (rough estimate)
refractive index :1.8000 (estimate)
storage temp. :2-8°C
solubility :H2O: 0.7 mg/mL
form :powder
pka :pKa 2.27 (Uncertain);9.25 (Uncertain)
color :white
Water Solubility :Soluble in 1M HCl at 50mg/ml. Soluble in water at 0.7mg/ml. Also soluble in DMSO
Merck :14,146
BCS Class :4,3
Stability :Stable. Incompatible with strong oxidizing agents.
InChIKey :MKUXAQIIEYXACX-UHFFFAOYSA-N
LogP :-0.617 (est)
CAS DataBase Reference :59277-89-3(CAS DataBase Reference)
IARC :3 (Vol. 76) 2000

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H320 Causes eye irritation Serious eye damage/eye irritation Category 2B Warning P264, P305+P351+P338,P337+P313
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.

Description

Acyclovir is a guanosine analog with antiviral activity in vitro against the herpes simplex viruses, varicella zoster virus, Epstein-Barr virus, cytomegalovirus, and human herpes virus 6 (ID50s = 0.1 - 63.1 μM). Acyclovir differs from most nucleoside analogs in that it contains only a partial nucleoside structure with an acyclic side chain. It diffuses freely into cells and is selectively converted into acyclo-guanosine monophosphate by a virus-specific thymidine kinase. During DNA replication, the phosphorylated form of acyclovir is preferentially incorporated into viral DNA, resulting in premature chain termination and inhibition of further activity of DNA polymerase.

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