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ChemicalBook >> CAS DataBase List >> 4-Hydroxy-N-[4-methoxy-7-(4-morpholinyl)-2-benzothiazolyl]-4-methyl-1-piperidinecarboxamide

4-Hydroxy-N-[4-methoxy-7-(4-morpholinyl)-2-benzothiazolyl]-4-methyl-1-piperidinecarboxamide

4-Hydroxy-N-[4-methoxy-7-(4-morpholinyl)-2-benzothiazolyl]-4-methyl-1-piperidinecarboxamide price.
  • $62 - $2400
  • Product name: 4-Hydroxy-N-[4-methoxy-7-(4-morpholinyl)-2-benzothiazolyl]-4-methyl-1-piperidinecarboxamide
  • CAS: 870070-55-6
  • MF: C19H26N4O4S
  • MW: 406.5
  • EINECS:
  • MDL Number:MFCD21642026
  • Synonyms:4-Hydroxy-N-[4-methoxy-7-(4-morpholinyl)-2-benzothiazolyl]-4-methyl-1-piperidinecarboxamide;SYN-115;4-Hydroxy-N-[4-methoxy-7-...;Tozadenant;4-hydroxy-N-(4-methoxy-7-morpholinobenzo[d]thiazol-2-yl)-4-methylpiperidine-1-carboxamide;Tozadenant (SYN-115);SYN-115 (Tozadenant);1-Piperidinecarboxamide, 4-hydroxy-N-[4-methoxy-7-(4-morpholinyl)-2-benzothiazolyl]-4-methyl-
20 prices
Selected condition：
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • Matrix Scientific
  • SynQuest Laboratories
Package
  • 5mg
  • 10MG
  • 25mg
  • 50mg
  • 100mg
  • 1g
  • 10mM(in 1mL DMSO)
  • 250mg
  • ManufacturerAK Scientific
  • Product number3711AC
  • Product description4-Hydroxy-N-(4-methoxy-7-morpholinobenzo[d]thiazol-2-yl)-4-methylpiperidine-1-carboxamide
  • Packaging250mg
  • Price$211
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0014160
  • Product descriptionSYN-115 95.00%
  • Packaging10MG
  • Price$255.15
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3885
  • Product descriptionTozadenant
  • Packaging10mM(in 1mL DMSO)
  • Price$132
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3885
  • Product descriptionTozadenant
  • Packaging10mg
  • Price$205
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3885
  • Product descriptionTozadenant
  • Packaging50mg
  • Price$585
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3885
  • Product descriptionTozadenant
  • Packaging250mg
  • Price$1439
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number28452
  • Product descriptionTozadenant
  • Packaging10mg
  • Price$62
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number28452
  • Product descriptionTozadenant
  • Packaging25mg
  • Price$113
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number28452
  • Product descriptionTozadenant
  • Packaging50mg
  • Price$194
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number28452
  • Product descriptionTozadenant
  • Packaging100mg
  • Price$330
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0359
  • Product descriptionTozadenant 98.65%
  • Packaging5mg
  • Price$144
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0359
  • Product descriptionTozadenant 98.65%
  • Packaging10mg
  • Price$216
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0359
  • Product descriptionTozadenant 98.65%
  • Packaging50mg
  • Price$648
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0359
  • Product descriptionTozadenant 98.65%
  • Packaging100mg
  • Price$1152
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC9332
  • Product descriptionTozadenant >98%
  • Packaging100mg
  • Price$600
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC9332
  • Product descriptionTozadenant >98%
  • Packaging250mg
  • Price$1200
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 3711AC 4-Hydroxy-N-(4-methoxy-7-morpholinobenzo[d]thiazol-2-yl)-4-methylpiperidine-1-carboxamide 250mg $211 2021-12-16 Buy
American Custom Chemicals Corporation API0014160 SYN-115 95.00% 10MG $255.15 2021-12-16 Buy
ApexBio Technology A3885 Tozadenant 10mM(in 1mL DMSO) $132 2021-12-16 Buy
ApexBio Technology A3885 Tozadenant 10mg $205 2021-12-16 Buy
ApexBio Technology A3885 Tozadenant 50mg $585 2021-12-16 Buy
ApexBio Technology A3885 Tozadenant 250mg $1439 2021-12-16 Buy
Cayman Chemical 28452 Tozadenant 10mg $62 2024-03-01 Buy
Cayman Chemical 28452 Tozadenant 25mg $113 2024-03-01 Buy
Cayman Chemical 28452 Tozadenant 50mg $194 2024-03-01 Buy
Cayman Chemical 28452 Tozadenant 100mg $330 2024-03-01 Buy
ChemScene CS-0359 Tozadenant 98.65% 5mg $144 2021-12-16 Buy
ChemScene CS-0359 Tozadenant 98.65% 10mg $216 2021-12-16 Buy
ChemScene CS-0359 Tozadenant 98.65% 50mg $648 2021-12-16 Buy
ChemScene CS-0359 Tozadenant 98.65% 100mg $1152 2021-12-16 Buy
DC Chemicals DC9332 Tozadenant >98% 100mg $600 2021-12-16 Buy
DC Chemicals DC9332 Tozadenant >98% 250mg $1200 2021-12-16 Buy

Properties

Density :1.374
storage temp. :Store at -20°C
solubility :insoluble in EtOH; insoluble in H2O; ≥20.35 mg/mL in DMSO
form :Powder
pka :14.95±0.20(Predicted)
color :White to off-white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Tozadenant is an adenosine A2A receptor antagonist (Kis = 11.5 and 6 nM for the human and rhesus monkey receptors, respectively). It increases the distance traveled and reduces contralateral asymmetry in the open field test in a rat model of Parkinson''s disease induced by 6-OHDA when administered at a dose of 30 mg/kg. Tozadenant (150 mg/kg) reverses locomotor deficits and restores novel object-stimulated locomotion in a marmoset model of MPTP-induced Parkinson''s disease.