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ChemicalBook >> CAS DataBase List >> (4S)-4-[3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]PYRROLIDIN-2-ONE

(4S)-4-[3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]PYRROLIDIN-2-ONE

(4S)-4-[3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]PYRROLIDIN-2-ONE price.
  • $74 - $1102
  • Product name: (4S)-4-[3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]PYRROLIDIN-2-ONE
  • CAS: 85416-75-7
  • MF: C16H21NO3
  • MW: 275.34
  • EINECS:
  • MDL Number:MFCD03093860
  • Synonyms:(4R)-4-[3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]PYRROLIDIN-2-ONE;(4S)-4-[3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]PYRROLIDIN-2-ONE;(S)-(+)-ROLIPRAM;(R)-(-)-ROLIPRAM;(4R)-4-(3-(Cyclopentyloxy)-4-methoxyphenyl)pyrrolidine-2-one;Rolipram (R)-(-)-;(4R)-(3-(Cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one;(R)-(-)-Rolipram
22 prices
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Brand
  • AK Scientific
  • Ambeed
  • Arctom
  • Axon Medchem
  • Biosynth Carbosynth
  • Chemenu
  • Chem-Impex
  • ChemScene
  • Crysdot
  • DC Chemicals
  • TCI Chemical
  • Tocris
  • TRC
Package
  • 10
  • 5mg
  • 1mg
  • 50
  • 10mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product numberP623
  • Product description(4R)-4-[3-(Cyclopentyloxy)-4-methoxyphenyl]pyrrolidin-2-one
  • Packaging1mg
  • Price$74
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA126491
  • Product description(R)-4-(3-(cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one 98%
  • Packaging50mg
  • Price$263
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS441946
  • Product description(R)-4-(3-(cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one 98%
  • Packaging100mg
  • Price$294
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS441946
  • Product description(R)-4-(3-(cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one 98%
  • Packaging250mg
  • Price$441
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS441946
  • Product description(R)-4-(3-(cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one 98%
  • Packaging1g
  • Price$1102
  • Updated2021-12-16
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  • ManufacturerAxon Medchem
  • Product numberAxon1229
  • Product description(R)-(-)-Rolipram 99%
  • Packaging10mg
  • Price$121
  • Updated2021-12-16
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  • ManufacturerAxon Medchem
  • Product numberAxon1229
  • Product description(R)-(-)-Rolipram 99%
  • Packaging50mg
  • Price$451
  • Updated2021-12-16
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  • ManufacturerBiosynth Carbosynth
  • Product numberFR65154
  • Product descriptionR-Rolipram
  • Packaging10mg
  • Price$75
  • Updated2021-12-16
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  • ManufacturerBiosynth Carbosynth
  • Product numberFR65154
  • Product descriptionR-Rolipram
  • Packaging50mg
  • Price$263
  • Updated2021-12-16
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  • ManufacturerChemenu
  • Product numberCM197834
  • Product description(R)-4-(3-(cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one 98%
  • Packaging50mg
  • Price$350
  • Updated2021-12-16
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  • ManufacturerChem-Impex
  • Product number38235
  • Product description(R)-(-)-Rolipram,98%(ChiralHPLC,HPLC) 98%(ChiralHPLC,HPLC)
  • Packaging10MG
  • Price$169.12
  • Updated2021-12-16
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  • ManufacturerChem-Impex
  • Product number38235
  • Product description(R)-(-)-Rolipram,98%(ChiralHPLC,HPLC) 98%(ChiralHPLC,HPLC)
  • Packaging50MG
  • Price$649.6
  • Updated2021-12-16
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  • ManufacturerChemScene
  • Product numberCS-3246
  • Product description(R)-(-)-Rolipram 99.91%
  • Packaging10mg
  • Price$110
  • Updated2021-12-16
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  • ManufacturerChemScene
  • Product numberCS-3246
  • Product description(R)-(-)-Rolipram 99.91%
  • Packaging50mg
  • Price$390
  • Updated2021-12-16
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  • ManufacturerCrysdot
  • Product numberCD31000590
  • Product description(R)-(-)-Rolipram 98+%
  • Packaging50mg
  • Price$358
  • Updated2021-12-16
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  • ManufacturerDC Chemicals
  • Product numberDC9584
  • Product description(R)-(-)-Rolipram >98%
  • Packaging100mg
  • Price$400
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific P623 (4R)-4-[3-(Cyclopentyloxy)-4-methoxyphenyl]pyrrolidin-2-one 1mg $74 2021-12-16 Buy
Ambeed A126491 (R)-4-(3-(cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one 98% 50mg $263 2021-12-16 Buy
Arctom AS441946 (R)-4-(3-(cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one 98% 100mg $294 2021-12-16 Buy
Arctom AS441946 (R)-4-(3-(cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one 98% 250mg $441 2021-12-16 Buy
Arctom AS441946 (R)-4-(3-(cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one 98% 1g $1102 2021-12-16 Buy
Axon Medchem Axon1229 (R)-(-)-Rolipram 99% 10mg $121 2021-12-16 Buy
Axon Medchem Axon1229 (R)-(-)-Rolipram 99% 50mg $451 2021-12-16 Buy
Biosynth Carbosynth FR65154 R-Rolipram 10mg $75 2021-12-16 Buy
Biosynth Carbosynth FR65154 R-Rolipram 50mg $263 2021-12-16 Buy
Chemenu CM197834 (R)-4-(3-(cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one 98% 50mg $350 2021-12-16 Buy
Chem-Impex 38235 (R)-(-)-Rolipram,98%(ChiralHPLC,HPLC) 98%(ChiralHPLC,HPLC) 10MG $169.12 2021-12-16 Buy
Chem-Impex 38235 (R)-(-)-Rolipram,98%(ChiralHPLC,HPLC) 98%(ChiralHPLC,HPLC) 50MG $649.6 2021-12-16 Buy
ChemScene CS-3246 (R)-(-)-Rolipram 99.91% 10mg $110 2021-12-16 Buy
ChemScene CS-3246 (R)-(-)-Rolipram 99.91% 50mg $390 2021-12-16 Buy
Crysdot CD31000590 (R)-(-)-Rolipram 98+% 50mg $358 2021-12-16 Buy
DC Chemicals DC9584 (R)-(-)-Rolipram >98% 100mg $400 2021-12-16 Buy

Properties

Melting point :132.0 to 136.0 °C
Boiling point :472.7±45.0 °C(Predicted)
Density :1.155±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :DMSO (Slightly), Methanol (Slightly)
pka :16.02±0.40(Predicted)
form :White to off-white solid.
color :Off-White

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H332 Harmful if inhaled Acute toxicity,inhalation Category 4 Warning GHS hazard pictograms P261, P271, P304+P340, P312
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

R-(-)-Rolipram is the R-entantiomer of rolipram. This compound has been shown to strongly inhibit the catalytic activities of PDE4 (phosphodiesterase 4), which is selective for cAMP, an important secondary messenger molecule in signal transduction. Experiments have revealed that high-affinity binding sites require residues within the catalytic domains and residues flanking the N-/C-terminal to the catalytic region of amino acids. Other studies suggest that the deactivation of PDE4 has been reported to affect other cellular functions.

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