- (R)-(-)-Rolipram
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- $39.00 / 2mg
-
2024-11-11
- CAS:85416-75-7
- Min. Order:
- Purity: 99.6%
- Supply Ability: 10g
- (R)-(-)-Rolipram
-
- $39.00 / 2mg
-
2024-11-11
- CAS:85416-75-7
- Min. Order:
- Purity: 99.6%
- Supply Ability: 10g
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| (4S)-4-[3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]PYRROLIDIN-2-ONE Basic information |
| (4S)-4-[3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]PYRROLIDIN-2-ONE Chemical Properties |
Melting point | 132.0 to 136.0 °C | Boiling point | 472.7±45.0 °C(Predicted) | density | 1.155±0.06 g/cm3(Predicted) | storage temp. | Sealed in dry,Store in freezer, under -20°C | solubility | DMSO (Slightly), Methanol (Slightly) | pka | 16.02±0.40(Predicted) | form | White to off-white solid. | color | Off-White |
HS Code | 2933.79.8500 | HazardClass | IRRITANT |
| (4S)-4-[3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]PYRROLIDIN-2-ONE Usage And Synthesis |
Uses | R-(-)-Rolipram is a phosphodiesterase IV (PDE4) inhibitor and anti-inflammatory agent with some antidepressant activity. It is the R isomer of (±)-Rolipram (R640040). Potent PDE4 inhibitor. | Definition | ChEBI: (-)-rolipram is the (R)-enantiomer of rolipram. It is an enantiomer of a (+)-rolipram. | Biological Activity | More active enantiomer of the PDE4 inhibitor rolipram (4-(3-(Cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one ); 2-10-fold more potent than the S-(+) enantiomer ((4S)-4-[3-(Cyclopentyloxy)-4-methoxyphenyl]pyrrolidin-2-one ). Also available as part of the Phosphodiesterase Inhibitor Tocriset™ . | storage | Room temperature |
| (4S)-4-[3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]PYRROLIDIN-2-ONE Preparation Products And Raw materials |
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