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2,3-???????-4-????????

2,3-???????-4-????????
2,3-???????-4-???????? ??? ???
?? ??:
884495-41-4
???:
2,3-???????-4-????????
???(??):
2,3-???????-4-????????
???:
2,3-Dichloropyridine-4-carboxaldehyde
???(??):
2,3-dichloroisonicotinaldehyde;2,3-dichloropyridine-4-carbaldehyde;2,3-Dichloropyridine-4-carboxaldehyde;2,3-Dichloro-4-pyridinecarboxaldehyde;4-Pyridinecarboxaldehyde, 2,3-dichloro-;2,3-dichloro-5-forMylpyridine-4-carboxylic acid;2,3-Dichloropyridine-4-carboxaldehyde ISO 9001:2015 REACH;2,3-Dichloropyridine-2,3-Dichloropyridine-4-carboxaldehyde4-carboxaldehyde
CBNumber:
CB9967298
???:
C6H3Cl2NO
??? ??:
176
MOL ??:
884495-41-4.mol

2,3-???????-4-???????? ??

???
94-96°
?? ?
262℃
??
1.488
???
112℃
?? ??
under inert gas (nitrogen or Argon) at 2-8°C
?? ?? (pKa)
-2.00±0.10(Predicted)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
?? ?? IRRITANT
HS ?? 2933399990
????(GHS): GHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ?? GHS hazard pictograms
??????:
P261 ??·?·??·???·??·...·????? ??? ????.
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P271 ?? ?? ??? ? ?? ???? ?????.
P280 ????/???/???/?????? ?????.
P302+P352 ??? ??? ??? ?? ????.
P304+P340 ???? ??? ??? ?? ??? ??? ???? ?? ??? ??? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
P312 ???? ??? ????(??)? ??? ????.
P332+P313 ?? ??? ??? ???? ??· ??? ????.
P337+P313 ?? ?? ??? ???? ???? ??· ??? ????.
P362 ??? ??? ?? ?? ?? ?????
P403+P233 ??? ??? ? ?? ?? ??? ???? ?????.
P405 ???? ?????.
P501 ...? ??? / ??? ?? ???.

2,3-???????-4-???????? C??? ??, ??, ??

??

2,3-Dichloroisonicotinaldehyde is used in preparation of spiroaminoindene piperidines as Shp2 phosphatase inhibitors for treatment of disorders associated with SHP2 deregulation.

2,3-???????-4-???????? ?? ?? ? ???

???

?? ??


2,3-???????-4-???????? ?? ??

???( 101)?? ??
??? ?? ??? ?? ?? ? ??
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